Thomas Peacock

Jan 14, 2025 | nature.com | Thomas Peacock |Wendy Barclay |Shengsong Xie

AbstractThe Eurasian avian-like (EA) H1N1 swine influenza virus (SIV) possesses the capacity to instigate the next influenza pandemic, owing to its heightened affinity for the human-type α-2,6 sialic acid (SA) receptor. Nevertheless, the molecular mechanisms underlying the switch in receptor binding preferences of EA H1N1 SIV remain elusive. In this study, we conduct a comprehensive genome-wide CRISPR/Cas9 knockout screen utilizing EA H1N1 SIV in porcine kidney cells.

Sep 24, 2024 | nature.com | Thomas Peacock |Ksenia Sukhova |James O. Lloyd-Smith |Anice C. Lowen

AbstractInfluenza A viruses have caused more documented global pandemics in human history than any other pathogen1,2. High pathogenicity avian influenza viruses belonging to the H5N1 subtype are a leading pandemic risk.

Jul 30, 2024 | lexology.com | Jonathan Marks |Beth Dobson |Thomas Peacock |Nick Bonsall |Caroline Phillips |James Costi

On 26 July the PRA published PS13/24, setting out feedback to CP24/23 - Funded reinsurance, together with a final supervisory statement (SS5/24) and accompanying Dear CEO letter. The new policy expectations set out in SS5/24 came into effect immediately. The Dear CEO letter requires firms using FundedRe to provide a number of pieces of information to the PRA by 31 October, including an assessment of the firm’s risk management practices against the expectations in the supervisory statement.

Jul 25, 2024 | m.farms.com | Will Stone |Thomas Peacock

By Will StoneFor nearly four months, the spread of bird flu in the nation’s dairy cattle has stoked fears that, if left unchecked, the virus could eventually unleash a pandemic. The recent cluster of human cases connected to poultry farms in Colorado only underscores that the threat remains real. Genetic sequencing of the virus collected from the sickened poultry workers closely resembles what’s circulating in dairy herds, suggesting that cattle somehow introduced the virus into the poultry flock.

Jul 24, 2024 | kuow.org | Will Stone |Thomas Peacock

For nearly four months, the spread of bird flu in the nation’s dairy cattle has stoked fears that, if left unchecked, the virus could eventually unleash a pandemic. The recent cluster of human cases connected to poultry farms in Colorado only underscores that the threat remains real. Genetic sequencing of the virus collected from the sickened poultry workers closely resembles what’s circulating in dairy herds, suggesting that cattle somehow introduced the virus into the poultry flock.