Vikaas S. Sohal

Nov 15, 2024 | nature.com | John Andrews |Kateryna Voitiuk |Alex Spaeth |Albert Wang |Jessica L. Sevetson |Kevin C. Donohue | +8 more

AbstractSeizures are made up of the coordinated activity of networks of neurons, suggesting that control of neurons in the pathologic circuits of epilepsy could allow for control of the disease. Optogenetics has been effective at stopping seizure-like activity in non-human disease models by increasing inhibitory tone or decreasing excitation, although this effect has not been shown in human brain tissue.

Dec 26, 2023 | mdpi.com | Jia Hu |Ruchi Malik |Vikaas S. Sohal |John L. Rubenstein

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.

May 3, 2023 | newspronto.com | Vikaas S. Sohal

akinbostanci/iStock via Getty Images PlusBeing flexible and learning to adapt when the world changes is something you practice every day. Whether you run into a new construction site and have to reroute your commute or download a new streaming app and have to relearn how to find your favorite show, changing familiar behaviors in response to new situations is an essential skill.

May 1, 2023 | bizzbuzz.news | Vikaas S. Sohal

To test the function of these long-range inhibitory connections, we observed mice performing a task that required them to learn a rule to receive a reward and then later adapt to a new rule in order to continue receiving the reward. In this task, mice dug in bowls to find hidden foodBeing flexible and learning to adapt when the world changes is something you practice every day.