Vivian Pae

Nov 18, 2024 | nature.com | Alton Barbehenn |Vivian Pae |Sannidhi Sarvadhavabhatla |Michael J Peluso |Jeffrey Martin |Frederick M. Hecht | +7 more

AbstractDespite antiretroviral therapy (ART), HIV persists in latently-infected cells (the HIV reservoir) which decay slowly over time. Here, leveraging >500 longitudinal samples from 67 people living with HIV (PLWH) treated during acute infection, we developed a mathematical model to predict reservoir decay from peripheral CD4 + T cells.