Weici Liu

1 month ago | molecular-cancer.biomedcentral.com | Xiaowen Xie |Weici Liu |Zhiyuan Yuan |Hanqing Chen |Wenjun Mao

The epigenome exhibits cell-type-specific variations and undergoes dynamic changes in response to environmental factors, regulating gene expression through multiple mechanisms [3]. Multiple factors-induced aberrant DNA methylation and histone modifications play a pivotal role in tumor initiation and progression by modulating the expression of tumor-associated genes and influencing processes such as cell death and metabolism (Fig. 2).