Wenjun Mao

Mar 7, 2025 | molecular-cancer.biomedcentral.com | Xiaowen Xie |Weici Liu |Zhiyuan Yuan |Hanqing Chen |Wenjun Mao

The epigenome exhibits cell-type-specific variations and undergoes dynamic changes in response to environmental factors, regulating gene expression through multiple mechanisms [3]. Multiple factors-induced aberrant DNA methylation and histone modifications play a pivotal role in tumor initiation and progression by modulating the expression of tumor-associated genes and influencing processes such as cell death and metabolism (Fig. 2).

Oct 31, 2023 | frontiersin.org | Wenjun Mao |Yu Yao |Qing Zhou

Brief medical historyA 58-year-old female patient was referred to the Department of Thoracic Surgery of Fujian Medical University Union Hospital due to “a lung nodule found in the left lower lobe” during a physical examination at the local Hospital A in Fujian Province, China on 23 March 2016. After various examinations, a main clinical diagnosis was made that confirmed the presence of a lung nodule in the left lower lobe.