Weiqiu Cheng

Oct 31, 2024 | nature.com | Yongsung Kim |Weiqiu Cheng |Chun-Seok Cho |Yongha Hwang |Yichen Si |Anna Park | +1 more

AbstractSpatial transcriptomics technologies aim to advance gene expression studies by profiling the entire transcriptome with intact spatial information from a single histological slide. However, the application of spatial transcriptomics is limited by low resolution, limited transcript coverage, complex procedures, poor scalability and high costs of initial setup and/or individual experiments.

Sep 12, 2024 | nature.com | Yichen Si |Yongha Hwang |Weiqiu Cheng |Chun-Seok Cho |Miguel Quirós |Jun Lee

AbstractSpatial transcriptomics (ST) technologies have advanced to enable transcriptome-wide gene expression analysis at submicron resolution over large areas. However, analysis of high-resolution ST is often challenged by complex tissue structure, where existing cell segmentation methods struggle due to the irregular cell sizes and shapes, and by the absence of segmentation-free methods scalable to whole-transcriptome analysis.

Apr 5, 2024 | digitalcommons.library.tmc.edu | Guy Hindley |Alexey Shadrin |Nadine Staples Parker |Weiqiu Cheng

To view the content in your browser, please download Adobe Reader or, alternately, you may Download the file to your hard drive. NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.

Apr 1, 2024 | biorxiv.org | Yongsung Kim |Weiqiu Cheng |Chun-Seok Cho |Yongha Hwang

AbstractSpatial transcriptomics (ST) technologies represent a significant advance in gene expression studies, aiming to profile the entire transcriptome from a single histological slide. These techniques are designed to overcome the constraints faced by traditional methods such as immunostaining and RNA in situ hybridization, which are capable of analyzing only a few target genes simultaneously.

Feb 20, 2024 | medrxiv.org | Nadine Staples Parker |Weiqiu Cheng |Guy Hindley |Kevin O'Connell

A.M.D. is a Founder of and holds equity in CorTechs Labs, Inc, and serves on its Scientific Advisory Board. A.M.D. is a member of the Scientific Advisory Board of Human Longevity, Inc. (HLI), and the Mohn Medical Imaging and Visualization Centre in Bergen, Norway. A.M.D. receives funding through a research agreement with General Electric Healthcare (GEHC).