Xiude Fan

Nov 6, 2024 | digitalcommons.library.tmc.edu | Xiaoqin Wu |Xiude Fan |Megan McMullen |Tatsunori Miyata

BACKGROUND AND AIMS: Mixed lineage kinase domain-like pseudokinase (MLKL), a key terminal effector of necroptosis, also plays a role in intracellular vesicle trafficking that is critical for regulating liver inflammation and injury in alcohol-associated liver disease (ALD). Although receptor interacting protein kinase 3 (Rip3)-/- mice are completely protected from ethanol-induced liver injury, Mlkl-/- mice are only partially protected.

Sep 25, 2024 | dx.doi.org | Zhao Dai |Xiaocong Pang |Nan Chen |Xiude Fan

May 30, 2024 | digitalcommons.library.tmc.edu | Xiude Fan |Junming Han |Enfa Zhao |Jiansong Fang

AbstractBreakthrough SARS-CoV-2 infections of vaccinated individuals are being reported globally, resulting in an increased risk of hospitalization and death among such patients. Therefore, it is crucial to identify the modifiable risk factors that may affect the protective efficacy of vaccine use against the development of severe COVID-19 and thus to initiate early medical interventions.

Apr 26, 2023 | frontiersin.org | Songqing He |Xiude Fan |Zunyi Zhang

Zunyi Zhang and Erlei Zhang*Research Laboratory and Hepatic Surgery Center, Department of Hepatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaHepatocellular carcinoma (HCC) is the most common type of liver cancer and has a high mortality rate worldwide. The percentage of HCC patients with vascular invasion at the time of initial HCC diagnosis is 10%–40%.

Mar 3, 2023 | cell.com | Xiude Fan |Metabolic Diseases |Junming Han |Enfa Zhao

Method detailsClassification of vaccination statusParticipants were considered vaccinated if they received one or more doses of vaccine 14 days or earlier before SARS-CoV-2 testing. Participants were considered as unvaccinated if they had never been vaccinated or received their first dose within 14 days before testing (Figures S1A and S1B). Participants were considered fully vaccinated after receiving the second dose prior to 14 days before testing. 2Sheikh A. Robertson C. Taylor B.