Xun Xu

Jan 18, 2025 | nature.com | Wei Gong |Xun Xu |Xiangui He

AbstractTo identify the role of fundus vascular arcades angle (VAA) in reflecting choroidal thickness (ChT) of highly myopic children and adolescents. Participants aged 5 to 18 yrs with high myopia (spherical equivalent, SE ≤ −5.0 D) were enrolled and followed up for one year from the Shanghai Child and Adolescent Large-scale Eye Study.

Jul 29, 2024 | nature.com | Xun Xu

AbstractProgressive dysfunction of the retinal pigment epithelium (RPE) and the adjacent photoreceptor cells in the outer retina plays a pivotal role in the pathogenesis of diabetic retinopathy (DR). Here, we observed a marked increase in oxidative stress-induced apoptosis in parallel with higher expression of telomeric protein TIN2 in RPE cells under hyperglycemia in vivo and in vitro.

Jun 21, 2024 | nature.com | Yahui Long |Kok Siong Ang |Raman Sethi |Lynn van Olst |Hang Xu |Lai Guan Ng | +3 more

AbstractAdvances in spatial omics technologies now allow multiple types of data to be acquired from the same tissue slice. To realize the full potential of such data, we need spatially informed methods for data integration. Here, we introduce SpatialGlue, a graph neural network model with a dual-attention mechanism that deciphers spatial domains by intra-omics integration of spatial location and omics measurement followed by cross-omics integration.

Mar 25, 2024 | pubs.acs.org | Han-Pu Liang |Chuan-Nan Li |Ran Zhou |Xun Xu

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Mar 25, 2024 | dx.doi.org | Han-Pu Liang |Chuan-Nan Li |Ran Zhou |Xun Xu

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX This article has not yet been cited by other publications.