Yan Wang

2 weeks ago | mdpi.com | Lingling Wei |Jinquan Wan |zhicheng Yan |Yan Wang

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1 month ago | bmccancer.biomedcentral.com | Miao Li |Rongxin Chen |Yan Wang

Patients diagnosed with unresectable ICC Between Jan 2022 and Sep 2023, who received either dual therapy (ICIs plus chemotherapy) or triple therapy (ICIs plus chemotherapy and Lenvatinib) as first-line treatment in Zhongshan Hospital, Fudan University were enrolled in the study.

1 month ago | nature.com | Lin Zhang |Yan Wang |Xinheng Zhao |Tong Cui

To investigate peripheral refraction and aberrations in myopic eyes after small-incision lenticule extraction (SMILE) surgery and to understand the relationship between visual symptoms and wide-field wavefront aberrations. A total of 28 patients with myopia and myopic astigmatism underwent SMILE surgery. Peripheral refraction and aberrations were measured both before and six months after surgery using a modified wide-field Shack–Hartmann wavefront (SHWS) sensor-based aberrometer. The peripheral refraction and aberrations from the axis (0°) to (15°) in both the horizontal and vertical directions were measured. A visual questionnaire was administered to assess visual quality before and six months after surgery. Post-surgery, peripheral relative refraction exhibited reduced hyperopia. The spherical aberration $${Z}_{4}^{0}$$ changed from 0.12 ± 0.11 μm before surgery to 0.24 ± 0.14 μm (t = 20.047, P = 0.000) after surgery on the optical axis(0°). Post-surgery, the spatial pattern of spherical aberration remained constant. Greater variability of peripheral aberrations was observed in the direction of the horizontal retina than in the vertical axis after surgery. Horizontal coma significantly increased after surgery and appeared to be more variable in the direction of the surperior region. $${Z}_{3}^{-1}$$ shifted from -0.03 ± 0.16 μm preoperatively to -0.12 ± 0.18 μm postoperatively (t = 0.580, P = 0.573), $${Z}_{3}^{1}$$ changed from 0.03 ± 0.22μm preoperatively to 0.37 ± 0.35 μm postoperatively (t = − 3.780, P = 0.003) on the central axis. The majority of patients were satisfied with the postoperative daytime vision; there was no significant deterioration in nighttime visual symptoms compared to preoperative levels. Our study demonstrated that SMILE significantly reduced peripheral refraction in myopic eyes, however with increased asymmetry along the vertical axis. Notably, the relationship between nighttime visual symptoms and large-field aberrations was not found to be significant.

Jan 19, 2025 | nature.com | Soumya Sarkar |Peter Newton |Yiru Zhu |Maheera Abdul Ghani |Hu Young Jeong |Yan Wang

AbstractGraphene-based spintronic devices require efficient spin injection, and dielectric tunnel barriers are typically used to facilitate spin injection. However, the direct growth of ultrathin dielectrics on two-dimensional surfaces is challenging and unreliable. Here we report spin injection in graphene lateral spin valves using ferromagnetic van der Waals contacts of indium and cobalt (In–Co), and without the deposition of dielectric tunnel barriers.

Jan 16, 2025 | mdpi.com | Ying Zhang |Yunfang Guan |Zongbo Li |Yan Wang

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.