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3 days ago | 
nature.com | Chongzhao You |Shimeng Guo |Tianwei Zhang |Xinheng He |Youwei Xu |Yi Jiang | +1 more
AbstractMaintaining pH homeostasis is critical for cellular function across all living organisms. Proton-sensing G protein-coupled receptors (GPCRs), particularly GPR4, play a pivotal role in cellular responses to pH changes. Yet, the molecular mechanisms underlying their proton sensing and activation remain incompletely understood. Here we present high-resolution cryo-electron microscopy structures of GPR4 in complex with G proteins under physiological and acidic pH conditions.
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1 month ago | 00007-5?rss=yes&sz=64)
cell.com | Zhenyu Wang |Li Tian |Yi Jiang |Lijun Ning |Xiaoqiang Zhu |Xuejie Chen | +13 more
KeywordsCrohn’ s diseaseustekinumabL-ornithineFaecalibacterium prausnitziiIL-12RB1EGR1IL-12/IL-23 signaling pathwayTh17 cellmulti-omicsmediation analysisGet full text accessLog in, subscribe or purchase for full access. References1. Danese, S. ∙ Vuitton, L. ∙ Peyrin-Biroulet, L. Biologic agents for IBD: practical insightsNat. Rev. Gastroenterol. Hepatol. 2015; 12:537-5452. Cao, Q. ∙ Chen, C. ∙ Gao, X. ...
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Feb 24, 2025 | 
rmi.org | Shuo Gao |Yi Jiang |Yujing Liu |Jun Xie
2024 Annual Report By Shuo Gao, Yi Jiang, Yujing Liu, Jun Xie Download the report below Ongoing power market reforms and improvements to green power procurement mechanisms have continued to boost China’s green power market. This rapid expansion has strengthened the foundation for corporations to leverage green power and Green Electricity Certificates (GECs) to meet both domestic and international compliance requirements. The report evaluates five green power procurement options within the...
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Jan 8, 2025 | 
dx.doi.org | Kejia You |Jiasong Lin |Zhen Wang |Yi Jiang
Functional Nanostructured Materials (including low-D carbon)January 8, 2025 Kejia You Strait Institute of Flexible Electronics (SIFE, Future Technologies), Fujian Key Laboratory of Flexible Electronics, Fujian Normal University and Strait Laboratory of Flexible Electronics (SLoFE), Fuzhou 350117, China Jiasong Lin Strait Institute of Flexible Electronics (SIFE, Future Technologies), Fujian Key Laboratory of Flexible Electronics, Fujian Normal University and Strait Laboratory of Flexible...
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Dec 17, 2024 | 
bookpage.com | Yi Jiang
Natalia Shaloshvili’s Pavlo Gets the Grumps is the sweetly funny story of an eventful day in the life of a grumpy kitten and the loved ones who attempt to jolly him out of his bad mood. Will their efforts be successful? First, while she and cranky little Pavlo eat their breakfast, Mama suggests a trip to the park. But a downcast Pavlo says no: “The swings are too swingy, the sandbox is too sandy, and . . . the slide is too SLIDEY!”Well, that’s hard to argue with, so Mama moves on: How about swimming?
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Oct 29, 2024 | 
nature.com | Yan Hu |Liang Ding |Qiyu Huang |Yi Jiang |Xiuxiang Li
Digital trade, as one of the vanguards of the global technological revolution and industrial transformation, empowers low-carbon economic cooperation on a global scale. This study based on panel data from 2007 to 2021 of 46 countries with varied development levels, constructed a multi-dimensional indicator system from six aspects: trade potential, digital infrastructure, digital innovation, digital skills and security, scale of digital trade, and digital trade environment, aim to measure the development level of digital trade and explore its impact on carbon emissions, followed by a heterogeneity analysis. The research results indicate that there are significant differences in the development levels of digital trade among countries with different economic strengths. Countries with stronger economic power and larger trade scales have a higher level of digital trade development, while less developed regions lag in digital trade. As the level of digital trade development increases, the impact of digital trade on carbon emissions will also change. Overall, digital trade exhibits a pronounced low-carbon effect, while its impact varies among countries with different development levels.
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Aug 27, 2024 | 
bookpage.com | Yi Jiang
Each Maghabol boy possesses a unique relationship to his cultural background. For example, Emil is an “assimilationist,” striving to replace his Filipino identity with an American one. On the other hand, his son, Chris, seeks out Filipino culture and tries to “self-educate” even though he’s coming from an outsider’s perspective due to his father’s parenting. How did you go about depicting these differences, with all their nuances?
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Jul 2, 2024 | 
bookpage.com | Yi Jiang
Get ready to fall in love with Max, the irrepressible elementary school narrator of That Always Happens Sometimes. He’s full of energy and enthusiasm that constantly erupts like a volcano.
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Jun 30, 2024 | 
sciencedirect.com | Tao Zeng |Yi Jiang
The rapid pace of industrialization, coupled with burgeoning population numbers and recurring droughts, has significantly amplified the global demand for clean water. This surge has led to an acute scarcity of sustainable water sources, a crisis further intensified by the fact that around 4 billion people worldwide are grappling with limited access to clean and sanitized water [1], [2].
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May 4, 2024 | 
arxiv.org | Yi Jiang |Abhronil Sengupta
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