Yize Li

3 days ago | nature.com | Wagma Caravan |Kazuhito Sato |Xiang Li |Yize Li |John Herndon |Maxim N. Artyomov | +1 more

AbstractThere is a sex bias in the incidence and progression of many kidney diseases. To better understand such sexual dimorphism, we integrated data from six platforms, characterizing 76 kidney samples from 68 mice at six developmental and adult time points, creating a molecular atlas of the mouse kidney across the lifespan for both sexes.

Nov 1, 2023 | nature.com | Alla Karpova |Yize Li |Austin N. Southard-Smith |Michael Iglesia |Reyka G. Jayasinghe |Matthew Wyczalkowski | +17 more

AbstractChromatin accessibility is essential in regulating gene expression and cellular identity, and alterations in accessibility have been implicated in driving cancer initiation, progression and metastasis1,2,3,4. Although the genetic contributions to oncogenic transitions have been investigated, epigenetic drivers remain less understood.