Yongwoo Lee

1 month ago | biorxiv.org | Yongwoo Lee |Priyojit Das |Michael Rosenberg |Roy Blum

AbstractUsing CLAP methodology, Guo et al. recently concluded that PRC2 is not an RNA binding protein (RBP). They suggest that prior findings were CLIP artifacts and argue against RNAs direct role in PRC2 regulation. Here, we re-analyze their raw datasets and reach contrary conclusions. Through an independent computational pipeline, we observe significant PRC2 enrichment throughout the transcriptome, including XIST. Applying the authors published computational pipeline also reaffirms PRC2 as an RBP.

Sep 20, 2024 | biorxiv.org | Yongwoo Lee |Roy Blum |Michael Rosenberg |Jeannie Lee

AbstractUsing halo-tagged PRC2 and CLAP methodology, Guo et al. recently came to the conclusion that PRC2 is not an RNA binding protein (RBP). They suggested that previous findings are CLIP artifacts and argue that RNA cannot play a direct role in PRC2 regulation. Here, we perform a re-analysis of the authors raw datasets and come to contrary conclusions. First, CLAP demonstrates significant PRC2 enrichment throughout the transcriptome, including in XIST Repeat A (RepA) motif.

Sep 18, 2024 | mdpi.com | Yongwoo Lee

1. IntroductionHomomorphic encryption (HE) is an encryption scheme that enables computations on encrypted data without requiring decryption. HE is widely used as a cryptographic back-end for privacy-preserving computations in various applications, such as secure multi-party computation, private set retrieval, and privacy-preserving machine learning [1,2,3].

Aug 19, 2024 | journals.plos.org | Yongwoo Lee |Gerd U Auffarth |Hyeck-Soo Son |Ramin Khoramnia

Loading metrics Open Access Peer-reviewedResearch Article Citation: Lee Y, Han SB, Auffarth GU, Son H-S, Khoramnia R, Choi CY, et al. (2024) Vertical implantable collamer lens as a novel method to increase rotational stability. PLoS ONE 19(8): e0308830. https://doi.org/10.1371/journal.pone.0308830Editor: Hidenaga Kobashi, Keio University School of Medicine, JAPANReceived: May 16, 2024; Accepted: July 22, 2024; Published: August 19, 2024Copyright: © 2024 Lee et al.

Nov 13, 2023 | artreview.com | Yongwoo Lee

‘Pan-shamanism’, spiritual mediums, hidden histories, deep trauma, time travel – are these the base materials that will reshape contemporary China? Wang Tuo is an artist interested in the possibility of a democratic revolution in China. His art – which spans film, performance, painting and drawing – meticulously interweaves his understanding of diverse times and spaces with fiction, mythology, archives, memory and instances of political turmoil.