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Jan 8, 2025 | 
mdpi.com | Yuan Zhou |Yang Wang |Bin Wang |Geran Wei
3.1. Datasets 3.1.1. Forest Inventory DataThe dataset comprised 3074 sites from the 9th National Forest Resources Inventory (2015) (Figure 1). For each site, the data included details on the individual trees (e.g., DBH, height, and species), site location, site area (0.06 ha), forest type, age group, forest health, and management practices.
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Sep 30, 2024 | 
nature.com | Yuan Zhou
AbstractThis study investigated how resting-state functional connectivity (rsFC) of the subgenual anterior cingulate cortex (sgACC) predicts antidepressant response in patients with major depressive disorder (MDD). Eighty-seven medication-free MDD patients underwent baseline resting-state functional MRI scans. After 12 weeks of escitalopram treatment, patients were classified into remission depression (RD, n = 42) and nonremission depression (NRD, n = 45) groups.
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Sep 7, 2024 | 
mdpi.com | Bei Li |Sheng Jiao |Yuan Zhou |Min Zhou
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Jun 15, 2024 | 
pericles.pericles-prod.literatumonline.com | Yuan Zhou |Shandong Academy |Engineering Chengdu |Qiang Zhang
Supporting Information Filename Description app55834-sup-0001-Supinfo.docxWord 2007 document , 39.7 MB DATA S1. Supplementary Information. REFERENCES 1, , , , , IEEE Rev. Biomed. Eng. 2020, 13, 261. 2, , , , , , J. Membr. Sci. 2022, 663, 121065. 3, , , , J. Membr. Sci. 2005, 249, 133. 4, , , Biomaterials 1999, 20, 1621. 5, , , Mater. Chem. Phys. 2020, 248, 122911. 6, , , , , , , , , , , , Carbohydr. Polym. 2020, 243, 116470. 7, Ther. Apher. Dial. 2003, 7, 108.
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Jun 11, 2024 | 
nature.com | Yuan Zhou
AbstractDifferences in clinical manifestations and biological underpinnings between Major Depressive Disorder (MDD) onset during adolescence and adulthood have been posited in previous studies, implying an influential role of age of onset (AOO) in the clinical subtyping and therapeutic approaches to MDD. However, direct comparisons between the two cohorts and their age-matched controls have been lacking in extant investigations.
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Mar 21, 2024 | 
mdpi.com | Mengyu Wang |Guanqun Wang |Yong Hu |Yuan Zhou
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
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Feb 22, 2024 | 
biorxiv.org | Chunfeng He |Yue Xu |Yuan Zhou |Jiayao Fan
AbstractGenetics-informed drug repositioning presents a streamlined and cost-efficient way to broaden therapeutic options. However, leveraging the full spectrum of molecular signatures remains underexplored. We introduce TReD (Transcriptome-informed Reversal Distance), integrating population-level disease signatures robust to reverse causality and cell-based drug-induced response profiles.
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Feb 4, 2024 | 
onlinelibrary.wiley.com | Shixia Ji |Yuan Zhou |Jiawen Chen |Minghui Yang
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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Nov 28, 2023 | 
genomemedicine.biomedcentral.com | Dan Zhou |Yuan Zhou |Yue Xu |Ran Meng |Eric R. Gamazon
The GWAS summary statistics for common variants were obtained from the Neale Lab (http://www.nealelab.is/uk-biobank) [19]. After quality control, variants with minor allele frequency (MAF) ≥ 0.05 were included. Up to 337,199 subjects were available, with the effective sample size varying with the trait. The genome-wide association statistics had been estimated using a linear model with sex and the first 10 principal components as covariates. We mapped the common variants to protein-coding genes.
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Oct 26, 2023 | 
biorxiv.org | Chunfeng He |Yue Xu |Yuan Zhou |Jiayao Fan
AbstractDrug repositioning presents a streamlined and cost-efficient way to expand the range of therapeutic possibilities. Furthermore, drugs with genetic evidence are more likely to progress successfully through clinical trials towards FDA approval. Exploiting these developments, single gene-based drug repositioning methods have been implemented, but approaches leveraging the entire spectrum of molecular signatures are critically underexplored.
