Yuxin Gu

Oct 23, 2024 | nature.com | Yuxin Gu |Song Jiang |Ming Chen |Min-Xin Guan |Siqi Sun |Zhihong Liu | +1 more

AbstractWe present SpliceTransformer (SpTransformer), a deep-learning framework that predicts tissue-specific RNA splicing alterations linked to human diseases based on genomic sequence. SpTransformer outperforms all previous methods on splicing prediction. Application to approximately 1.3 million genetic variants in the ClinVar database reveals that splicing alterations account for 60% of intronic and synonymous pathogenic mutations, and occur at different frequencies across tissue types.

Sep 10, 2024 | highschool.latimes.com | Yuxin Gu

Have you ever experienced sudden relief from anxiety when greeted by your furry best friend? Raising a pet can bring much more joy to your life. However, turns out, they can also be beneficial for improving ADHD symptoms and helping promote mindfulness. Attention deficit hyperactivity disorder (ADHD), is one of the most common mental disorders, especially in children and teens. It is caused by . It can lead to the inability to keep focus, excessive movement, and act without thinking or control.