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Oct 30, 2024 | 
dx.doi.org | Zhihong Liu |Yiming Bai |Zhe Wang |Caiqin Yan
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Oct 23, 2024 | 
nature.com | Yuxin Gu |Song Jiang |Ming Chen |Min-Xin Guan |Siqi Sun |Zhihong Liu | +1 more
AbstractWe present SpliceTransformer (SpTransformer), a deep-learning framework that predicts tissue-specific RNA splicing alterations linked to human diseases based on genomic sequence. SpTransformer outperforms all previous methods on splicing prediction. Application to approximately 1.3 million genetic variants in the ClinVar database reveals that splicing alterations account for 60% of intronic and synonymous pathogenic mutations, and occur at different frequencies across tissue types.
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Aug 10, 2024 | 
dovepress.com | Zhihong Liu |Xiaofang Liang |Yu ZHANG |Wenbo Deng
Back to Journals » Infection and Drug Resistance » Volume 17 Authors Liu Z, Liang X, Zhang Y , Deng W , Wang Y, Lu Z , Liu Q, Wei L Received 10 August 2024Accepted for publication 9 October 2024 Published 21 October 2024Volume 2024:17 Pages 4539—4556 DOI https://doi.org/10.2147/IDR.S490998Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 2 Editor who approved publication: Prof.
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Aug 9, 2024 | 
nature.com | Qing Xie |Zhihong Liu
AbstractEssential oils (EOs) are complex and susceptible to environmental conditions, they have a wide range of biological activities and are often used to differentiate between similar species. In this study, gas chromatography-mass spectrometry (GC–MS) coupled with chemometric analysis was applied to systematically analyse and evaluate EOs constituents and antioxidant activity of six Chinese Cupressaceae taxa (Platycladus orientalis Franco, P. orientalis Franco ‘Sieboldii’, P.
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Jun 5, 2024 | 
nature.com | Gang Wang |Zhihong Liu |Yuanhua Huang
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-48282-5, published online 10 May 2024In this article, Chen Cheng and Gang Wang should have been denoted as equally contributing authors. The original article has been corrected.
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May 9, 2024 | 
nature.com | Gang Wang |Zhihong Liu |Yuanhua Huang
AbstractDisease modeling with isogenic Induced Pluripotent Stem Cell (iPSC)-differentiated organoids serves as a powerful technique for studying disease mechanisms. Multiplexed coculture is crucial to mitigate batch effects when studying the genetic effects of disease-causing variants in differentiated iPSCs or organoids, and demultiplexing at the single-cell level can be conveniently achieved by assessing natural genetic barcodes.
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Jul 23, 2023 | 
pubs.acs.org | Yuying Zhang |Zhen Li |Wei Hu |Zhihong Liu
There are several corrections to the original paper:(1) On page 10302, line 13 (in the abstract), “a hundred-fold enhancement” should be replaced with “a 167-fold enhancement”. (2) On page 10303, line 35 (right column), “from 600 to 800 nm” should be replaced with “from 570 to 800 nm”. (3) In the captions of Figures 2–4, “10 μM” should be replaced with “20 μM”.
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Jul 3, 2023 | 
nature.com | Zhihong Liu
AbstractSince Liangzhu culture was recognised as the earliest monarchical period in the history of China, its vitality has been acknowledged both by the public and archaeologists in China and worldwide.
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May 24, 2023 | 
onlinelibrary.wiley.com | Lede Lin |Huiling Chen |Yu Chi Liu |Zhihong Liu
Abstract Adrenal venous sampling (AVS) is thought to be the gold standard for primary aldosteronism (PA) subtype discrimination, during which the application of adrenocorticotropic hormone (ACTH) arouses heated debate. We aimed to identify the effect of ACTH on AVS and surgical outcomes. After propensity score matching (PSM), a total of 220 patients diagnosed with PA and completed AVS were included (110 without ACTH stimulation and 110 with ACTH stimulation).
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Feb 21, 2023 | 
link.aps.org | Zhihong Liu |Hunan Normal |Jialin Zhang |Hongwei Yu
Abstract We make a detailed comparison between entanglement harvesting for uniformly accelerated detectors in vacuum and static ones in a thermal bath at the Unruh temperature and find that, for a small energy gap relative to the Heisenberg energy of the detectors, static detectors in the thermal bath can harvest more entanglement and possess a comparatively larger harvesting-achievable range than the uniformly accelerated ones; however, as the energy gap grows sufficiently large, the...
