-
3 weeks ago | 
mdpi.com | Yuxuan Chen |Zhong Tang |Shiguo Wang |Yang Liu
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Jan 15, 2025 | 
science.org | Yuxuan Chen |Xiaohong Chen |Yao Zhang |Meng Wang |Minqi Yang |Xiaojie Yan | +6 more
-
Jan 15, 2025 | 
science.org | Ewa Ziółkowska |Yuxuan Chen |Matthew Jansen |Wesley Brandao
Editor’s summaryNeuronal ceroid lipofuscinosis type 1 and 2 (CLN1 and CLN2) are pediatric neurodegenerative disorders caused by loss-of-function mutations in PPT1 and TPP1, respectively. Although gastrointestinal problems are common for both forms of neuronal ceroid lipofuscinosis (NCL), it has been unclear how the enteric nervous system is affected by the disease. Here, Ziółkowska et al. report diminished bowel function in mouse models of CLN1 and CLN2.
-
Nov 5, 2024 | 
mdpi.com | Yuxuan Chen |Ce Wang |Yuan Hui |Nirav Shah
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Jul 21, 2024 | 
mdpi.com | Junjie Wu |Wei Yu |Zhuo Xu |Yuxuan Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Jul 4, 2024 | 
nature.com | Kexin Su |Yuxuan Chen |Yuan Ping |Zhen Gu
AbstractFully targeted mRNA therapeutics necessitate simultaneous organ-specific accumulation and effective translation. Despite some progress, delivery systems are still unable to fully achieve this. Here, we reformulate lipid nanoparticles (LNPs) through adjustments in lipid material structures and compositions to systematically achieve the pulmonary and hepatic (respectively) targeted mRNA distribution and expression.
-
Apr 25, 2024 | 
link.aps.org | Yuxuan Chen |Sun Yat-sen |Jian Yuan |Biao Wang
Charge density waves (CDWs) in two-dimensional materials have received great attention due to their intriguing properties, yet the microscopic evolution process of CDW transition and its impact on charge transport remain to be fully understood. Herein we employed density-functional theory calculations to ascertain the richness of CDW phases in VX2 (X=S, Te) originated from electron-phonon coupling.
-
Jul 6, 2023 | 
onlinelibrary.wiley.com | Yuxuan Chen |Yanan Li
Abstract We consider the global existence of the solution for nonlinear damped wave equations at arbitrary positive initial energy, that is, E ( 0 ) > 0 $E(0)>0$ . It is well known from a work of G. Filippo and S. Marco [Ann. Inst. H. Poincaré Anal. Non Linéaire, 2006], that which initial data with high energy make the model exists global solutions is still an interesting question. Here, we give it an affirmative answer.
-
May 13, 2023 | 
pubs.acs.org | Yuxuan Chen |Yuan Ping
ConspectusClustered, regularly interspaced, short palindromic repeat (CRISPR)/associated protein 9 (CRISPR/Cas9) is emerging as a powerful genome-editing tool, enabling precise and targeted modifications of virtually any genomic sequence in living cells. These technologies have potential therapeutic applications for cancers, metabolic diseases, and genetic disorders. However, several major challenges hinder the full realization of their potential.
-
Apr 20, 2023 | 
arxiv.org | Zheng Sun |Yuxuan Chen |Lei Ju
arXiv:2304.10088 (eess) Download a PDF of the paper titled Towards the Universal Defense for Query-Based Audio Adversarial Attacks, by Feng Guo and 2 other authors Download PDF Submission history From: Yuxuan Chen [ view email] [v1] Thu, 20 Apr 2023 04:50:02 UTC (862 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer () Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart Citations?) Code, Data, Media DagsHub Toggle DagsHub...
