Jian Yuan

Oct 17, 2024 | mdpi.com | Tao Liu |Shuli Cheng |Jian Yuan

1. IntroductionRecently, due to ongoing improvements in remote sensing image technology, achieving high-quality semantic segmentation of these images has emerged as a fundamental and the most talked about task in remote sensing image processing. This technique is essential for applications including urban planning [1], land cover classification [2], and land use planning [3].The main goal of semantic segmentation is to label each pixel of the input image with its category.

Aug 28, 2024 | science.org | Loretah Chibaya |Ying Liu |Jie Ma |Feng Wang |Dan Zhang |Luping Liu | +17 more

Editor’s summaryCD8+ T cells are a critical part of antitumor immunity and depend on metabolites including glucose to maintain their function. Here, Liu et al. have evaluated targeting glucose transport 10 (GLUT10) as a way to increase CD8+ T cell function by disrupting the competitive binding of lactic acid that increased glucose uptake, thereby increasing proliferation and antitumor capacity.

Apr 25, 2024 | link.aps.org | Yuxuan Chen |Sun Yat-sen |Jian Yuan |Biao Wang

Charge density waves (CDWs) in two-dimensional materials have received great attention due to their intriguing properties, yet the microscopic evolution process of CDW transition and its impact on charge transport remain to be fully understood. Herein we employed density-functional theory calculations to ascertain the richness of CDW phases in VX2 (X=S, Te) originated from electron-phonon coupling.

Sep 22, 2023 | nature.com | Jian Yuan |Jian-dong Jiang

AbstractCSCs (Cancer stem cells) with distinct metabolic features are considered to cause HCC (hepatocellular carcinoma) initiation, metastasis and therapeutic resistance. Here, we perform a metabolic gene CRISPR/Cas9 knockout library screen in tumorspheres derived from HCC cells and find that deletion of SCARB2 suppresses the cancer stem cell-like properties of HCC cells.

Apr 3, 2023 | nature.com | Yu Chen |Jian Yuan |Ying Jiang

Extended Data Fig. 1 USP15 interacts with PARP1 in a PAR-independent manner. (a) Screening of putative PARP1-interacting DUBs using 60 vectors encoding different DUBs. Vectors encoding HA-tagged DUBs and GFP-tagged PARP1 were cotransfected into HEK293 cells. After 24 h, cells were harvested for a co-IP assay with beads coated with GFP nanobodies prior to Western blot analysis with the indicated antibodies.