Zibo Li

Sep 10, 2024 | digitalcommons.library.tmc.edu | Tian Tian |Zibo Li |Yicheng Wang |Penghui Jia

AbstractThe maintenance of lysosome homeostasis is crucial for cell growth. Lysosome-dependent degradation and metabolism sustain tumor cell survival. Here, we demonstrate that CCDC50 serves as a lysophagy receptor, promoting tumor progression and invasion by controlling lysosomal integrity and renewal. CCDC50 monitors lysosomal damage, recognizes galectin-3 and K63-linked polyubiquitination on damaged lysosomes, and specifically targets them for autophagy-dependent degradation.

Oct 31, 2023 | dx.doi.org | Yilin Liu |Zibo Li |Yang Xu |Xia Xu

RETURN TO ARTICLES ASAPPREVSurfaces, Interfaces...Surfaces, Interfaces, and ApplicationsNEXT Yilin Liu Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Lab of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, 100190 Beijing, China University of Chinese Academy of Sciences, 100049 Beijing, China , Zibo Li Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Lab of Colloid, Interface and Chemical...

Oct 17, 2023 | mdpi.com | Zibo Li |Guohua Zhang |Yubo Li |Wenjun Zhou

6. DiscussionIn coal mining, rock bursts occur due to the stress state of the coal seam and rock stratum and their occurrence conditions. The thickness of the coal seam varies significantly in the local area, and the stress state of the surrounding rock in this area is correlated with the variation in coal thickness and the mechanical properties of the roof and floor.