AHA/ASA Journals

5 days ago | ahajournals.org | Howard C Herrmann |Toby Rogers

Research ArticleOpen AccessCirculation: Cardiovascular InterventionsThe SMART trial (URL: https://www.clinicaltrials.gov; Unique identifier: NCT04722250) is an international, prospective, postmarket, randomized trial designed to compare the outcomes after transcatheter aortic valve replacement with a supraannular self-expanding valve (SEV) versus an intraannular balloon-expandable valve (BEV) in patients with symptomatic severe aortic stenosis and a small aortic annulus (≤430 mm2).

3 weeks ago | ahajournals.org | Andrew Perry

Research ArticleOpen AccessNonstandard Abbreviations and AcronymsADFalternate day fastingFHSFramingham Heart StudyIHTGintrahepatic triglycerideMASLDmetabolic dysfunction‐associated steatotic liver diseaseMRI‐PDFFmagnetic resonance imaging proton density fat fractionPCAprincipal component analysisClinical Perspective•We identified a proteomic signature associated with hepatic steatosis content that tracked with changes in hepatic steatosis over an interventional study of alternate day fasting.

1 month ago | ahajournals.org | Jose Romero |José Romero

PCNSV With Spinal Cord Involvement: A 40-Year Single-Center StudySalvarani et al report the largest study of primary central nervous system vasculitis involving the spinal cord carried over 40 years. Diagnosis of primary central nervous system vasculitis was confirmed either by biopsy, imaging, or angiography, and all cases with spinal cord involvement had biopsy-proven diagnosis. Differences were compared with primary central nervous system vasculitis cases without spinal cord involvement.

1 month ago | ahajournals.org | Simon Lee

Research ArticleOpen AccessNonstandard Abbreviations and AcronymsCAcoronary arteryIKDRInternational Kawasaki Disease RegistryKDKawasaki diseasemaxCAZmaximum Z score in any CA branchMIS‐Cmultisystem inflammatory syndrome in childrenClinical Perspective•Although common, coronary artery involvement is mild and rapidly resolves in multisystem inflammatory syndrome in children. •Similar to the other cardiovascular findings, management can be supportive with good long‐term outcomes.

1 month ago | ahajournals.org | Gaby Weissman |Toby Rogers

Information & AuthorsPublished In Circulation: Cardiovascular InterventionsHistoryReceived: 18 September 2024Accepted: 17 March 2025Published online: 22 April 2025PermissionsRequest permissions for this article. Keywordsaortaaortic valvehumanstomographytranscatheter aortic valve replacementSubjectsDisclosuresDr Gordon received institutional research grant support from Edwards Lifesciences.