Royal Society of Chemistry

1 day ago | pubs.rsc.org | Nan Zhang |Huaqi Zhang |Yan Xu |Guifa Wang

Neuroprotective effect of folic acid by maintaining DNA stability and mitochondrial homeostasis through ATM/CHK2/P53/PGC-1α pathway in Alcohol-exposed mice Excessive drinking leads to alcoholic brain injury, which is characterized by neuroinflammation, cognitive decline and motor dysfunction. These pathological features are closely related to chromosome DNA damage and mitochondrial dysfunction.

3 days ago | pubs.rsc.org | Juiz de Fora |Nicholas Farrell |Virginia Commonwealth

SI-PPC-induced modulation of heparin/heparanase binding affinity: a steered molecular dynamics approach† We report a steered molecular dynamics (SMD) investigation into how substitution-inert polynuclear platinum complexes (SI-PPCs) influence the binding affinity between heparan sulphate (HS) and the enzyme heparanase.

5 days ago | pubs.rsc.org | Kun Huang |Mohan Wang |Yujiao Wang |Shan Wang

The Promotion of Nitrite and Nitrate Conversion into Ammonia by Improving *H Utilization via the Construction of Dual Active Centers Although the research on electrochemical reduction of nitrite and nitrate to ammonia (NO3RR/NO2RR) catalysts has made significant progress, the process of economical and sustainable neutral electrolytes is still scarce.

6 days ago | pubs.rsc.org | Rakesh Kumar |Baghendra Singh |Apparao Draksharapu

Molecular Ru(II) complexes with universal pH hydrogen evolution performance The development of efficient and robust hydrogen evolution reaction (HER) catalysts that operate across a wide pH range is critical for advancing sustainable hydrogen production. Previously a series of molecular complexes have been immobilized on solid supports to get efficient HER activity. However, achieving HER activity with molecular complexes in universal pH still remains challenging.

6 days ago | pubs.rsc.org | Subham Sau |Krishna Das |Arunabha Thakur

Visible-light triggered Cu-catalyzed C─H bond activation to afford isocoumarin and isoquinolinone scaffolds at room temperature We report a visible light induced copper salt mediated novel approach for the synthesis of a series of isocoumarin and isoquinolinone scaffolds including 27 new compounds at room temperature for the first time in excellent yields without any additive, ligand template, oxidant or external photocatalyst.