Evidence-Based Dentistry

Evidence-based dentistry (EBD) focuses on using the most up-to-date scientific research to make informed decisions in dental care. This method emphasizes the importance of integrating relevant scientific information with the dentist's own professional knowledge and skills. By adopting EBD, dental professionals can keep pace with the latest advancements in treatment options, ensuring that patients receive the best possible care. In the 1990s, a new educational framework was created to merge current research with clinical practice, enabling healthcare providers to improve patient outcomes. This initiative was spearheaded by Gordon Guyatt and the Evidence-Based Medicine Working Group at McMaster University in Ontario, Canada.

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Exclusive: a Nature analysis signals the beginnings of a US science brain drain

2 days ago | nature.com | Jack Leeming

Researchers in the United States are seeking career opportunities abroad as President Donald Trump’s administration slashes science funding and workforce numbers, finds an analysis of Nature’s jobs-board data. Data from the Nature Careers global science jobs platform show that US scientists submitted 32% more applications for jobs abroad between January and March 2025 than during the same period in 2024. At the same time, the number of US-based users browsing jobs abroad increased by 35%.
The variability of Antarctic dense water overflows can be observed from space - Communications Earth & Environment

3 days ago | nature.com | Matthis Auger |Paul Spence |Adele K. Morrison

AbstractAround the margins of Antarctica, dense waters formed on the continental shelf are exported to oceanic depths. This overflow of dense waters to the abyss ventilates the ocean, and is vital to the global overturning circulation.
Brand-new colour created by tricking human eyes with laser

5 days ago | nature.com | Elizabeth Gibney

Five people have been able to perceive a colour never before seen by human eyes, after researchers used lasers and tracking technology to selectively activate certain cells in their retinas. The blue-greenish hue has an intensity, or ‘saturation’, outside the natural range of colours seen by humans. The work is “amazing technically” and an “extraordinary achievement”, says Kimberly Jameson, a colour-vision scientist at the University of California, Irvine.
‘Totally broken’: how Trump 2.0 has paralysed work at US science agencies

6 days ago | nature.com | Dan Garisto |Jeff Tollefson

As the administration of President Donald Trump continues its campaign to reshape the US government with spending cuts and mass lay-offs, some scientists still employed at government agencies say that their work has become impossible.
Sowing solutions: my quest to save Kenya’s maize from a devastating invader

1 week ago | nature.com | Linda Nordling

“I’m a plant pathologist at the Kenya Agriculture and Livestock Organization in Machakos, east of Nairobi. For more than a decade, I’ve been working on a sustainable way to control Striga, a parasitic weed that damages farmers’ crops here in Kenya. This photo, taken in January this year, shows me holding a Striga plant in a maize field in western Kenya, where Striga infested 73% of farms in 2009. It steals nutrients through the crops’ roots, sometimes destroying entire harvests.
India to begin construction of gravitational wave project

1 week ago | nature.com | Subhra Priyadarshini

After nearly a decade of planning, lobbying, and fine-tuning, the Indian government has greenlit the full-scale construction of the Laser Interferometer Gravitational Wave Observatory-India (LIGO-India), a world-class gravitational wave observatory. With a formal tender for civil and vacuum works issued this week and a ₹1600 crore (~$190 million USD) construction budget now unlocked, India’s contribution to the global hunt for gravitational waves is shifting from blueprints to brick and steel.
Structured evaluation processes are associated with higher levels of employee belonging - Scientific Reports

1 week ago | nature.com | A. Chyei Vinluan |Austin Smith |Edward H. Chang

AbstractIn both a field study (N = 28,064) and a preregistered vignette experiment (N = 800), we find that more perceived structure in evaluation processes is associated with higher levels of belonging for employees. More structured evaluation processes increase perceptions of procedural justice and of genuine commitment to diversity, equity, and inclusion—both of which are tied to a greater sense of belonging.
Producing aryl halides from lignin - Nature Communications

1 week ago | nature.com | Wei Li |Shujun Li |Zhijun CHEN

AbstractLignin represents the most abundant biomass resource, which contains aromatic units. Lignin refinery is a promising, sustainable alternative for the production of aromatic chemicals. However, depolymerization and transformation of lignin into aryl halides, which are indispensable chemicals in both the academic and industrial communities, remain challenging.
Back to the drawing board for anhedonia drugs

1 week ago | nature.com | Asher Mullard

NEWS 16 April 2025 Johnson & Johnson has discontinued development of aticaprant for depression with anhedonia, a blow to hopes for drugs for ‘domains’ of psychiatric disorders. Psychiatric drug developers have for years been pointing to kappa-opioid receptor (KOR) antagonists as the poster children for a new era in psychiatric medicine.
Winner, winner, lab-made dinner! Team grows nugget-sized chicken chunk

1 week ago | nature.com | Nicola Jones

Researchers have created what they think is the largest chunk of meat grown in the laboratory yet, thanks to a designer ‘circulatory system’ that delivers nutrients and oxygen into the growing tissue. Shoji Takeuchi, a biohybrid system engineer at the University of Tokyo, and colleagues report growing a single piece of chicken that measures 7 centimetres long, 4 centimetres wide and 2.25 centimetres thick. Weighing in at 11 grams, it is about the size of a chicken nugget.