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Nov 20, 2024 | 
mdpi.com | André Carvalho |Lara Toledo Cordeiro
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Oct 24, 2024 | 
nature.com | André Carvalho |Alberto Hipólito
AbstractIntegrons are key elements in the rise and spread of multidrug resistance in Gram-negative bacteria. These genetic platforms capture cassettes containing promoterless genes and stockpile them in arrays of variable length. In the current integron model, expression of cassettes is granted by the Pc promoter in the platform and is assumed to decrease as a function of its distance.
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Oct 6, 2024 | 
probonoaustralia.com.au | André Carvalho
CF Together is a national organisation dedicated to advancing progress for people living with cystic fibrosis (CF).
Our purpose is to drive progress for all people living with CF in Australia by enabling the CF community to access the best care and support, advocating for change, advancing treatment and finding a cure.
We have recently released a new strategic plan, including a rebrand and a change of name from Cystic Fibrosis Community Care to CF Together.
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Oct 5, 2024 | 
biorxiv.org | Louna Fruchard |Anamaria Babosan |André Carvalho |Manon Lang
AbstractTgt is the enzyme modifying the guanine (G) in tRNAs with GUN anticodon to queuosine (Q). tgt is required for optimal growth of Vibrio cholerae in the presence of sub-lethal aminoglycoside concentrations. We further explored here the role of the Q34 in the efficiency of codon decoding upon tobramycin exposure.
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Sep 30, 2024 | 
mdpi.com | André Carvalho |Renato Pereira |David M. Pereira |Loic Hilliou
1. IntroductionTissue and bone engineering, and ultimately regenerative and personalized medicine, seem within reach in a near future thanks to the development of smart functional biomaterials [1,2,3]. Hydrogels are archetypical biomaterials: bulk materials with nanostructuring and high-water content, reminiscent of the extracellular matrix; adjustable rheological properties; biocompatibility and responsiveness to environmental cues [4].
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Sep 26, 2024 | 
biorxiv.org | Mathias Cobbaut |André Carvalho |Marina Ivanova |Christopher P. Earl
AbstractThe mutually antagonistic kinase-substrate relationship between the apical aPKC-Par6 heterodimer and the basolateral substrate Lgl is key to the establishment and maintenance of cell polarity across metazoa. Although aPKC-Par6 can phosphorylate Lgl at three serine sites to exclude it from the apical domain, paradoxically, aPKC-Par6 and Lgl can also form a stable kinase-substrate complex whose function remains unclear and with conflicting roles proposed for Par6.
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Sep 24, 2024 | 
pubs.aip.org | André Carvalho |Av. Esperança |Campus Samambaia |Al. Ingá
Nowadays, AISI 304 stainless steel plays a crucial role in industry. However, stainless steel exhibits limited wear resistance as it is used in parts with relative motion. Laser treatment emerges as a promising approach to improve its superficial properties. Using a laser as a heat source presents unique properties for heating surfaces, as the first atomic layers of the material absorb the radiation from the laser beam.
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Aug 26, 2024 | 
mdpi.com | Gleice Kelly Barbosa |André Carvalho
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Aug 24, 2024 | 
onlinelibrary.wiley.com | Valeria Gomes |Porto Universities |André Carvalho |Loic Hilliou
Supporting Information Filename Description psc3650-sup-0001-Supporting_Information.docxWord 2007 document , 1.8 MB Figure S1. 1H NMR spectrum of Nap-l-Lys(Cbz)-z-ΔAbu-OH (1), in DMSO-d6. Figure S2. Temperature variation over time of the synthesized manganese ferrite nanoparticles in water (0.1 wt%), under different magnetic field strengths and frequencies. Table S1. Calculated SLP $$ SLP $$ for the synthesized manganese ferrite nanoparticles in water (0.1 wt%). Figure S3.
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Aug 20, 2024 | 
nature.com | Cassiano Gustavo Messias |Fabio Alves |Mariane S. Reis |Amanda P. Belluzzo |Camila B. Quadros |Diego Silva | +8 more
AbstractThe Brazilian Amazon Satellite Monitoring Program (PRODES Amazonia) tracks forest loss in the Brazilian Amazon but excludes about 6.6% ( ~ 280,000 km²) of non-forest vegetation (NF). Here we developed the PRODES NF system to address this gap by adapting the well-established methodology of PRODES Amazonia.
