Andrew Rambaut

1 week ago | cell.com | Jonathan Pekar |Spyros Lytras |Mahan Ghafari |Andrew Magee |Edyth Parker |Yu Wang | +13 more

Keywords molecular epidemiology sarbecoviruses virus evolution phylogeography Introduction Horseshoe bats (Rhinolophus spp.) are the main hosts of the Sarbecovirus subgenus1 (genus Betacoronavirus, family Coronaviridae) and, likely via virus transmission through transient intermediate species, were the source of SARS-CoV (referred to hereafter as SARS-CoV-1, now extinct) and SARS-CoV-2.2,3,4 Since the first emergence of SARS-CoV-1 in Guangzhou, Guangdong Province, in 2002 and SARS-CoV-2...

May 8, 2024 | nature.com | Lorenzo Subissi |Homa Attar Cohen |Laith J Abu-Raddad |Erik Alm |Wendy Barclay |Jinal N. Bhiman | +17 more

The World Health Organization framework for tracking SARS-CoV-2 variants has been updated to reflect the continued evolution of the virus; this framework could be adapted for other emerging respiratory diseases with epidemic and pandemic potential.

Dec 29, 2023 | academic.oup.com | Andrew Rambaut

The question of the origin of the Covid-19 pandemic is inherently scientific, even though its broader political context and implications cannot be ignored (Gostin and Gronvall, 2023). Uncertainty remains regarding the exact conditions of SARS-CoV-2’s emergence and spillover to humans. The level of available details and the amount of data on the early days of Covid-19 are, however, remarkable compared to other emerging diseases, and in particular to SARS (Xu et al., 2004; Keusch et al., 2022).

Sep 14, 2023 | nature.com | Chimaobi Chukwu |David King |Afolabi Akinpelu |Paolo Ribeca |Rebecca Sumner |Andrew Rambaut | +4 more

AbstractThe 2022 global mpox outbreak raises questions about how this zoonotic disease established effective human-to-human transmission and its potential for further adaptation. The 2022 outbreak virus is related to an ongoing outbreak in Nigeria originally reported in 2017, but the evolutionary path linking the two remains unclear due to a lack of genomic data between 2018, when virus exportations from Nigeria were first recorded, and 2022, when the global mpox outbreak began.

Jul 15, 2023 | biorxiv.org | Leo Featherstone |Andrew Rambaut |Sebastian Duchêne |Wytamma Wirth

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