Anya Topiwala

May 20, 2024 | medrxiv.org | Anya Topiwala |Daniel F Levey |Hang Zhou |Joseph D. Deak

The authors have declared no competing interest. This research used data from the Million Veteran Program and was supported by funding from the Department of Veterans Affairs Office of Research and Development, Million Veteran Program Grant #I01CX001849, and the VA Cooperative Studies Program (CSP) study #575B, and MVP025. This publication does not represent the views of the Department of Veterans Affairs or the United States Government. AT is supported by the Wellcome Trust (216462/Z/19/Z).

Dec 13, 2023 | nature.com | Pek Kei Im |Anya Topiwala |Zhengming Chen |Iona Y. Millwood |Steven Bell

AbstractAlcohol-related liver disease (ARLD) represents a major public health burden. Identification of high-risk individuals would allow efficient targeting of public health interventions. Here, we show significant interactions between pattern of drinking, genetic predisposition (polygenic risk score, PRS) and diabetes mellitus, and risk of incident ARLD, in 312,599 actively drinking adults in UK Biobank.

Apr 15, 2023 | infobae.com | Anya Topiwala

Los telómeros son tapas protectoras al final de los cromosomas que se acortan progresivamente con cada división celular. Su desgaste es un marcador del envejecimiento biológico y puede aumentar la susceptibilidad a enfermedades relacionadas con la edad, incluida la enfermedad de Alzheimer. Sin embargo, el mecanismo por el cual el envejecimiento celular acelerado aumenta el riesgo de enfermedad neuropsiquiátrica no está claro.