Christopher E. Mason

2 months ago | bmcglobalpublichealth.biomedcentral.com | Santa Rosa |Materials Engineering |Coral Gables |Environmental Biotechnology |Martin Hölzer |Daniel Desiró | +10 more

ReferencesKo KKK, Chng KR, Nagarajan N. Metagenomics-enabled microbial surveillance. Nat Microbiol. 2022;7:486–96. Article  CAS  PubMed  Google Scholar  Karthikeyan S, Levy JI, De Hoff P, Humphrey G, Birmingham A, Jepsen K, et al. Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission. Nature. 2022;609:101–8. Article  CAS  PubMed  PubMed Central  Google Scholar  Tisza M, Javornik Cregeen S, Avadhanula V, Zhang P, Ayvaz T, Feliz K, et al.

Nov 16, 2024 | link.springer.com | Joseph W. Guarnieri |JangKeun Kim |Douglas Wallace |Christopher E. Mason |Masafumi Muratani |Afshin Beheshti

AbstractTo be able to understand how spaceflight can affect human biology, there is a need for maximizing the amount of information that can be obtained from experiments flown to space. Recently there has been an influx of data obtained from astronauts through multi-omics approaches based on both governmental and commercial spaceflight missions. In addition to data from humans, mitochondrial specific data is gathered for other experiments from rodents and other organisms that are flown in space.

Apr 3, 2024 | nature.com | Jie Li |Christopher R Chin |Cem Meydan |Pedro Farinha |Yiyue Jiang |Martin Rivas | +9 more

AbstractDespite regulating overlapping gene enhancers and pathways, CREBBP and KMT2D mutations recurrently co-occur in germinal center (GC) B cell-derived lymphomas, suggesting potential oncogenic cooperation. Herein, we report that combined haploinsufficiency of Crebbp and Kmt2d induces a more severe mouse lymphoma phenotype (vs either allele alone) and unexpectedly confers an immune evasive microenvironment manifesting as CD8+ T-cell exhaustion and reduced infiltration.

Nov 7, 2023 | nature.com | S. Narayanan |Victoria Zaksas |Jiwoon Park |Saswati Das |Pedro M. Moraes-Vieira |Christopher E. Mason | +1 more

AbstractCOVID-19, the disease caused by SARS-CoV-2, has caused significant morbidity and mortality worldwide. The betacoronavirus continues to evolve with global health implications as we race to learn more to curb its transmission, evolution, and sequelae. The focus of this review, the second of a three-part series, is on the biological effects of the SARS-CoV-2 virus on post-acute disease in the context of tissue and organ adaptations and damage.

Sep 1, 2023 | slguardian.org | Igor Tulchinsky Christopher E. Mason |Igor Tulchinsky |Christopher E. Mason

The following excerpts are adapted from the authors’ recent book, The Age of Prediction, published by MIT PressHumanity has entered a new era. We are now living in a world that is increasingly wired by billions of predictive algorithms, a world in which almost everything can be predicted and risk and uncertainty appear to be diminishing in almost all areas of life. We are living longer, thanks to advances in health care and precision medicine.