Ct Usa

Jan 10, 2025 | biorxiv.org | Claudia Mimoso |Hanneke Vlaming |Karen Adelman |Ct Usa

AbstractThe eukaryotic genome is broadly transcribed by RNA polymerase II (RNAPII) to produce protein-coding messenger RNAs (mRNAs) and a repertoire of non-coding RNAs (ncRNAs). Whereas RNAPII is very processive during mRNA transcription, it terminates rapidly during synthesis of many ncRNAs, particularly those that arise opportunistically from accessible chromatin at gene promoters or enhancers.

Jul 25, 2024 | academic.oup.com | Ct Usa

Many types of networks, such as co-expression or ChIP-seq-based gene-regulatory networks, provide useful information for biomedical studies. However, they are often too full of connections and difficult to interpret, forming “indecipherable hairballs”. To address this issue, we propose that a Bayesian network can summarize the core relationships between gene expression activities.

Apr 11, 2024 | academic.oup.com | Ct Usa |Steven Kleinstein

Predictive biological signatures provide utility as biomarkers for disease diagnosis and prognosis, as well as prediction of responses to vaccination or therapy. These signatures are identified from high-throughput profiling assays through a combination of dimensionality reduction and machine learning techniques.

Jun 19, 2023 | agsjournals.onlinelibrary.wiley.com | Kristin Phillips |Mi Usa |Ct Usa |Marcia C. Mecca

MODELS OF GERIATRIC CARE, QUALITY IMPROVEMENT, AND PROGRAM DISSEMINATION Abstract Background Virtual collaborative models are a practical way to implement a supportive environment for multi-team learning. In this project, we aimed to describe the processes and outcomes of a virtual deprescribing collaborative that facilitated implementation of deprescribing interventions around the country.