Dag Alnæs

Dec 17, 2023 | nature.com | Lars T. Westlye |Thomas Bjella |Linn Sofie Sæther |Ingrid Melle |Ole A. Andreassen |Dag Alnæs | +2 more

AbstractThere is substantial cognitive heterogeneity among patients with schizophrenia (SZ) and bipolar disorders (BD). More knowledge about the magnitude and clinical correlates of performance variability could improve our understanding of cognitive impairments. Using double generalized linear models (DGLMs) we investigated cognitive mean and variability differences between patients with SZ (n = 905) and BD spectrum disorders (n = 522), and healthy controls (HC, n = 1170) on twenty-two variables.

Feb 18, 2023 | nature.com | Tobias Kaufmann |Srdjan Djurovic |Ole A. Andreassen |Dag Alnæs

AbstractThe 15q11.2 BP1-BP2 copy number variant (CNV) is associated with altered brain morphology and risk for atypical development, including increased risk for schizophrenia and learning difficulties for the deletion. However, it is still unclear whether differences in brain morphology are associated with neurodevelopmental or neurodegenerative processes.