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Jul 28, 2024 | 
nature.com | Shahar Bracha |Athena Economides |Daniel Walsh |Adriano Aguzzi |Lilach Sheiner
AbstractDelivering macromolecules across biological barriers such as the blood–brain barrier limits their application in vivo. Previous work has demonstrated that Toxoplasma gondii, a parasite that naturally travels from the human gut to the central nervous system (CNS), can deliver proteins to host cells. Here we engineered T.
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Jun 11, 2024 | 
pubs.usgs.gov | Kate Burgener |Stuart Siegfried Lichtenberg |Daniel Walsh |Heather N. Inzalaco
Prion diseases such as scrapie, bovine spongiform encephalopathy (BSE), and chronic wasting disease (CWD) affect domesticated and wild herbivorous mammals. Animals afflicted with CWD, the transmissible spongiform encephalopathy of cervids (deer, elk, and moose), shed prions into the environment, where they may persist and remain infectious for years. These environmental prions may remain in soil, be transported in surface waters, or assimilated into plants.
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Jun 5, 2024 | 
sbnonline.com | Daniel Walsh
While in business school at Case Western Reserve University, my professors described various business organizational structures: corporations, sole proprietorships, joint ventures (JV). They noted that establishing a joint venture is the most difficult structure to execute. Not one to shy away from a challenge (or a glutton for punishment), I’ve spent most of my career forging new JVs with dozens of operating partners.
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May 26, 2024 | 
mdpi.com | Stuart Siegfried Lichtenberg |Daniel Walsh |Kate Burgener |Heather N. Inzalaco
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
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Apr 1, 2024 | 
journals.plos.org | Daniel Walsh |Judy R Rees |Surabhi Mehra |PLOS Pathogens
Loading metrics Open Access Peer-reviewedResearch Article Citation: Walsh DJ, Rees JR, Mehra S, Bourkas MEC, Kaczmarczyk L, Stuart E, et al. (2024) Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease. PLoS Pathog 20(4): e1012087. https://doi.org/10.1371/journal.ppat.1012087Editor: Suzette A.
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Mar 27, 2024 | 
smarthomeperfected.com | Daniel Walsh
A “smart” home is recognized for its ability to adjust to changing conditions in your house by utilizing sensors. These sensors consistently monitor different elements like temperature, humidity, light, UV, noise, smoke, water, and motion, contributing to efficient response handling.
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Mar 3, 2024 | 
sbnonline.com | Daniel Walsh
“Your new comfort zone is being out of your comfort zone.” Our team embraced this mindset while starting a new line of business in a bank in the 1990s. We had a solid plan and sufficient resources, but turning a great idea into a sustainable business is never certain. We focused on core strengths and always putting our clients first, embraced the uncertainty that fueled our creativity and problem-solving skills, and positioned the business for resilient growth.
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Feb 29, 2024 | 
smarthomeperfected.com | Daniel Walsh
It’s impossible to figure out which appliances are hogging energy just by reading your energy bill. Enter the whole home energy monitor; a superhero to help you understand your home energy usage. Follow our guide to learn more about the best smart home energy monitor! 9.8 9.7 9.1 Energy monitors really pay for themselves. They empower home owners with real-time data and insights on how to reduce their energy usage and save money.
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Feb 1, 2024 | 
environmental-expert.com | Daniel Walsh
Mating a 671hp (500kW) 2.4L twin turbocharged V6 engine to a Bosch hybrid battery drive and new transmission meant that engine and gearbox wear needed to be constantly monitored throughout the race.
A new racing fuel with a high ethanol content can also lead to unexpected issues, primarily excessive fuel dilution, which, if left unchecked, would result in viscosity loss, leading to premature cylinder and crankcase wear.
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Oct 9, 2023 | 
psychiatrist.com | Daniel Walsh |Nora K. Horick |Maura DiSalvo |Chloe Hutt Vater
ABSTRACTObjective: Some individuals with attention-deficit/hyperactivity disorder (ADHD) may not tolerate or adequately respond to currently available treatments. This study examined whether solriamfetol could have a favorable pattern of effects and tolerability as a treatment for ADHD in adults.
