Ezequiel Dantas

Jun 11, 2024 | nature.com | Eliah G. Overbey |JangKeun Kim |Braden T. Tierney |Jiwoon Park |Deena Najjar |Remi Klotz | +30 more

AbstractSpaceflight induces molecular, cellular, and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space1-6. Yet, current frameworks for aerospace medicine are nascent and lag far behind advancements in precision medicine on Earth, underscoring the need for rapid development of space medicine databases, tools, and protocols.

Jun 10, 2024 | nature.com | JangKeun Kim |Braden T. Tierney |Eliah G. Overbey |Ezequiel Dantas |Jiwoon Park |Fei Wu | +16 more

AbstractSpaceflight induces an immune response in astronauts. To better characterize this effect, we generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data for the SpaceX Inspiration4 (I4) mission crew. We found that 18 cytokines/chemokines related to inflammation, aging, and muscle homeostasis changed after spaceflight.

May 23, 2024 | onlinelibrary.wiley.com | Henning Tim Langer |Shakti Ramsamooj |Ezequiel Dantas |Anirudh Murthy

1 INTRODUCTION The cancer-associated cachexia syndrome (CACS) is a frequently occurring adverse effect of lung cancer, and independently predicts poor quality of life, reduced anticancer treatment tolerance, and reduced life expectancy in patients.1, 2 CACS is characterized by loss of adipose and muscle tissue.

Aug 2, 2023 | biorxiv.org | Ezequiel Dantas |Henning Tim Langer |Shakti Ramsamooj |Anirudh Murthy

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May 18, 2023 | biorxiv.org | Ying Liu |Ezequiel Dantas |Miriam Ferrer |Yifang Liu

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