Geoffroy Gagliardi

Apr 5, 2024 | nature.com | Elisenda Bueichekú |Ibai Diez |Geoffroy Gagliardi |Kayden J. Mimmack |Jorge Sepulcre

AbstractUnawareness is a behavioral condition characterized by a lack of self-awareness of objective memory decline. In the context of Alzheimer’s Disease (AD), unawareness may develop in predementia stages and contributes to disease severity and progression. Here, we use in-vivo multi-modal neuroimaging to profile the brain phenotype of individuals presenting altered self-awareness of memory during aging.

Aug 1, 2023 | nature.com | Geoffroy Gagliardi |Elena Rodriguez-Vieitez |Ibai Diez |Cristina Lois |Reisa Sperling

AbstractNon-invasive diffusion-weighted imaging (DWI) to assess brain microstructural changes via cortical mean diffusivity (cMD) has been shown to be cross-sectionally associated with tau in cognitively normal older adults, suggesting that it might be an early marker of neuronal injury.