Gerome Breen

Jan 14, 2025 | nature.com | Lachlan Gilchrist |Thomas P. Spargo |Rebecca Green |David Howard |Jackson G. Thorp |Brett N. Adey | +25 more

AbstractDepression is a risk factor for the later development of Alzheimer’s disease (AD), but evidence for the genetic relationship is mixed. Assessing depression symptom-specific genetic associations may better clarify this relationship.

Nov 20, 2024 | nature.com | Gerome Breen

NEWS AND VIEWS 20 November 2024 In rare diseases, rare mutations have long been thought of as the only contributor. Genetic analyses of people with such conditions now suggest that the effects of common genetic variants can stack up and contribute to disease risk. Rare conditions that affect a person's neurodevelopment are thought to arise almost exclusively from rare genetic mutations that greatly disrupt gene function.

Oct 15, 2024 | nature.com | Emma Dempster |Eilis Hannon |Diego Quattrone |Edoardo Spinazzola |Zhikun Li |Charlotte Gayer-Anderson | +17 more

AbstractThe rising prevalence and legalisation of cannabis worldwide have underscored the need for a comprehensive understanding of its biological impact, particularly on mental health. Epigenetic mechanisms, specifically DNA methylation, have gained increasing recognition as vital factors in the interplay between risk factors and mental health.

May 16, 2024 | kcl.ac.uk | Thalia C. Eley |Gerome Breen |Ewan Carr

Wellcome has awarded over £4.8m for researchers to predict individual outcomes following psychological treatments for anxiety, and to identify genetic and cognitive mechanisms.

May 7, 2024 | kcl.ac.uk | Gerome Breen

On Wednesday 24 May 2024, Gerome Breen delivered his inaugural lecture as Professor of Psychiatric Genetics at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN). Derived from The Hitchhiker's Guide to the Galaxy, Professor Breen’s lecture “A Geneticist’s Guide to the Galaxy of Mental Health” explored his journey from farming and working in his father’s butcher shop, to becoming Professor of Psychiatric Genetics at King’s College London.