Glenda M Halliday

Jun 30, 2024 | movementdisorders.onlinelibrary.wiley.com | Jacqueline Burré |Robert Edwards |Glenda M Halliday |Anthony E Lang

α-Synuclein (αSyn) pathology is a major feature of Parkinson's disease (PD), and the occurrence of pathogenic variants in the SNCA gene1-12 or multiplication of its locus13, 14 supports a possible causative role of αSyn in PD. Yet the nature of this role has long been a matter of debate due to unclear αSyn-mediated mechanisms of cell dysfunction, degeneration, and death.

Nov 7, 2023 | onlinelibrary.wiley.com | Matthew C. Kiernan |Glenda M Halliday |Dominic Rowe |Rachel Tan

No abstract is available for this article. 1, , , et al. Treatment with the copper compound CuATSM has no significant effect on motor neuronal pathology in patients with ALS. Neuropathol Appl Neurobiol. 2023; 49(4):e12919. doi:10.1111/nan.12919 2, , . CuII(atsm) significantly decreases microglial reactivity in patients with sporadic ALS. Neuropathol Appl Neurobiol. 2023; 49(5):e12938. doi:10.1111/nan.12938 3, , , , , . Review: microglia in motor neuron disease. Neuropathol Appl Neurobiol.