Hugh Mitchell

Feb 12, 2025 | nature.com | Bryon S. Donohoe |Kelsey Ramírez |Hugh Mitchell |Samuel O. Purvine |Benjamin P Bowen |Katherine Louie | +3 more

AbstractWhite-rot fungi are efficient organisms for the mineralization of lignin and polysaccharides into CO2 and H2O. Despite their biotechnological potential, WRF metabolism remains underexplored. Building on recent findings regarding the utilization of lignin-related aromatic compounds as carbon sources by WRF, we aimed to gain further insights into these catabolic processes.

Jan 9, 2025 | dx.doi.org | Jason McDermott |Jon Jacobs |Nathaniel Merrill |Hugh Mitchell

Journal of Proteome ResearchCite this: J. Proteome Res. 2025, XXXX, XXXClick to copy citationCitation copied!. This publication is available under these Terms of Use. Learn about these metricsArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.

Dec 4, 2024 | nature.com | James M. Fulcher |Hugh Mitchell |David Degnan |Lisa M. Bramer |Ronald Moore |Wei-Jun Qian | +1 more

AbstractSingle-cell multiomics provides comprehensive insights into gene regulatory networks, cellular diversity, and temporal dynamics. Here, we introduce nanoSPLITS (nanodroplet SPlitting for Linked-multimodal Investigations of Trace Samples), an integrated platform that enables global profiling of the transcriptome and proteome from same single cells via RNA sequencing and mass spectrometry-based proteomics, respectively.

Jul 4, 2024 | biorxiv.org | James M. Fulcher |Hugh Mitchell |Sarah Williams |Kristin M Engbrecht

AbstractSingle-cell multiomics provides comprehensive insights into gene regulatory networks, cellular diversity, and temporal dynamics. Here, we introduce nanoSPLITS (nanodroplet SPlitting for Linked-multimodal Investigations of Trace Samples), an integrated platform that enables global profiling of the transcriptome and proteome from same single cells using RNA sequencing and mass spectrometry-based proteomics, respectively.