Ronald Moore

Dec 4, 2024 | nature.com | James M. Fulcher |Hugh Mitchell |David Degnan |Lisa M. Bramer |Ronald Moore |Wei-Jun Qian | +1 more

AbstractSingle-cell multiomics provides comprehensive insights into gene regulatory networks, cellular diversity, and temporal dynamics. Here, we introduce nanoSPLITS (nanodroplet SPlitting for Linked-multimodal Investigations of Trace Samples), an integrated platform that enables global profiling of the transcriptome and proteome from same single cells via RNA sequencing and mass spectrometry-based proteomics, respectively.

Jan 31, 2024 | nature.com | Ruonan Wu |Nathalie Muñoz |Aivett Bilbao |Rosalie K. Chu |Carrie D. Nicora |Daniel Orton | +7 more

AbstractThe leaf-cutter ant fungal garden ecosystem is a naturally evolved model system for efficient plant biomass degradation. Degradation processes mediated by the symbiotic fungus Leucoagaricus gongylophorus are difficult to characterize due to dynamic metabolisms and spatial complexity of the system.