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4 weeks ago | 
nature.com | Ruyi Li |Jun Liu |Kai Zhu |An Pan |Yunfei Liao
AbstractA comprehensive assessment of combined modifiable risk factors with common complications of type 2 diabetes (T2D) is lacking, and the potential role of proteomics remains unclear. Here, we examine the associations of cardiovascular health (CVH) score and degree of risk factor control with common diabetic complications using data from the UK Biobank (n = 14,102). Furthermore, we explore the mediation effects of plasma proteomics in a subset with proteomic data (n = 1287).
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1 month ago | 
science.org | Ayato Sato |Jun Liu |Libo Shan |Kenichiro Itami |Naoyuki Uchida |Asraa Ziadi | +10 more
A small compound uncovers the MAP kinase homeostasis–based signal specificity between plant development and immunity.
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1 month ago | 
firstlinks.com.au | Rudi Filapek-Vandyck |James Gruber |Harry Chemay |Jun Liu
Professor Robert Deutsch: "This has got to be the best set of articles on economic and financial matters. Always something worthwhile reading in Firstlinks. Thankyou"Reader: "It's excellent so please don't pollute the content with boring mainstream financial 'waffle' and adverts for stuff we don't want!"Steve: "The best that comes into our world each week.
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2 months ago | 
onlinelibrary.wiley.com | Jun Liu |Prevention Beijing |Yan Wu |George F. Gao
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description imr70000-sup-0001-TableS1.xlsxExcel 2007 spreadsheet , 2.8 MB Table S1. Amino acid substitutions and deletions in the representative SARS-CoV-2 variants/sub-variants. imr70000-sup-0002-TableS2.xlsxExcel 2007 spreadsheet , 57.7 KB Table S2. List of the epitopes of major anti-NTD mAbs. imr70000-sup-0003-TableS3.xlsxExcel 2007 spreadsheet , 74.8 KB Table S3.
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2 months ago | 
mdpi.com | Jun Liu |Peng Zhang |Xiaofei Wang
1. IntroductionClimate change is one of the most severe environmental challenges faced globally, and its negative impacts are continuously spreading and intensifying worldwide [,]. The primary cause of global warming is the continuous increase in greenhouse gasses, mainly carbon dioxide, methane, nitrous oxide, hydrofluorocarbons, perfluorocarbons, and sulfur hexafluoride.
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Jan 22, 2025 | 
science.org | Yijie Zhou |Saqlain Raza |Thanh Nguyen |Thanh Hoàng Nguyễn |Thành Dương Nguyễn |Jiawei Zhou | +14 more
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Jan 15, 2025 | 
mdpi.com | Jun Liu |Chenggang Zhou |Haoyuan Wei |Jie Pi
1. IntroductionGlobal meat production shows a steady growth trend, with the Food and Agriculture Organization of the United Nations (FAO) data indicating that global meat production in 2024 is expected to reach 371 million tons (carcass weight equivalent). To meet the growing demand for meat, the meat processing industry faces significant challenges, requiring innovative technological solutions and efficient quality control strategies.
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Jan 15, 2025 | 
onlinelibrary.wiley.com | Chang Liu |Yuanchao Wang |Jun Liu |Ziyi WANG
Conflicts of Interest The authors declare no conflicts of interest. References 1, , and , “Effect of Mn and Mg Reinforcing Particles on Physico-Mechanical Behavior of Close-Cell Al Metal Foam for Energy Absorption Material,” Journal of Engineering and Applied Science 71, no. 1 (2024): 50. 2, , and , “Energy Absorption Performance of Open-Cell Aluminum Foam and Its Application in Landing Buffer System,” Journal of Materials Engineering and Performance 30, no. 8 (2021): 1–14.
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Jan 10, 2025 | 
nature.com | Tilman Schneider-Poetsch |Yuichi Shichino |Céline Moriou |Daniel Romo |Jun Liu |Takuhiro Ito | +3 more
AbstractNatural products have a long history of providing probes into protein biosynthesis, with many of these compounds serving as therapeutics. The marine natural product girolline has been described as an inhibitor of protein synthesis. Its precise mechanism of action, however, has remained unknown. The data we present here suggests that girolline is a sequence-selective modulator of translation factor eIF5A.
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Jan 9, 2025 | 
nature.com | Jun Liu |Li Wang |Reuben Samson
AbstractContinuously emerging SARS-CoV-2 Omicron subvariants pose a threat thwarting the effectiveness of approved COVID-19 vaccines. Especially, the protection breadth and degree of these vaccines against antigenically distant Omicron subvariants is unclear. Here, we report the immunogenicity and efficacy of a bivalent mRNA vaccine, PTX-COVID19-M1.2 (M1.2), which encodes native spike proteins from Wuhan-Hu-1 (D614G) and Omicron BA.2.12.1, in mouse and hamster models.
