Katherine Munson

Jan 29, 2025 | nature.com | Mitchell R. Vollger |Kiara C. Eldred |Elliott Swanson |Elizabeth Blue |Katherine Munson |Jessica Ogawa | +4 more

AbstractResolving the molecular basis of a Mendelian condition remains challenging owing to the diverse mechanisms by which genetic variants cause disease. To address this, we developed a synchronized long-read genome, methylome, epigenome and transcriptome sequencing approach, which enables accurate single-nucleotide, insertion–deletion and structural variant calling and diploid de novo genome assembly.

Dec 3, 2024 | ospreyobserver.com | Katherine Munson

BY Katherine Munson, Lead Conservation Education Coordinator Q: How can I save water when preparing holiday meals? A: Defrost frozen foods in the refrigerator or the microwave instead of running hot water over them. Rinse vegetables and fruits in a sink or pan filled with water instead of under running water. This water can then be reused to water houseplants. A running faucet can use approximately 2 gallons of water per minute.

Nov 22, 2023 | ospreyobserver.com | Katherine Munson

By Katherine Munson, Lead Communications CoordinatorSouthwest Florida experienced its driest summer rainy season in 26 years, so it’s a good time to remember that water conservation is more important than ever during the dry season. Leading into the holiday season, water plays a role in everything from food preparation to the cleanup process. Q: How can I save water when preparing holiday meals? A: Defrost frozen foods in the refrigerator or the microwave instead of running hot water over them.

Aug 23, 2023 | nature.com | Arang Rhie |Savannah Hoyt |Dylan Taylor |Nicolas Altemose |Paul W. Hook |Sergey Koren | +37 more

AbstractThe human Y chromosome has been notoriously difficult to sequence and assemble because of its complex repeat structure that includes long palindromes, tandem repeats and segmental duplications1,2,3. As a result, more than half of the Y chromosome is missing from the GRCh38 reference sequence and it remains the last human chromosome to be finished4,5.

May 10, 2023 | nature.com | Mitchell R. Vollger |Philip C. Dishuck |Katherine Munson |Glennis A. Logsdon |David Porubsky |Benedict Paten | +1 more

AbstractSingle-nucleotide variants (SNVs) in segmental duplications (SDs) have not been systematically assessed because of the limitations of mapping short-read sequencing data1,2. Here we constructed 1:1 unambiguous alignments spanning high-identity SDs across 102 human haplotypes and compared the pattern of SNVs between unique and duplicated regions3,4.