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Jan 6, 2025 | 
onlinelibrary.wiley.com | Weijin Wang |Ryo Tachibana |Kailin Zhang |Kelvin Lau
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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Dec 11, 2024 | 
mdpi.com | Kelvin Lau |Carl Lowenberger |Sanam Meraj |Phillip Phung
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Oct 26, 2024 | 
link.springer.com | David Hacker |Kelvin Lau |Florence Pojer |Laurence Durrer |Soraya Quinche |Ludovic Delisle
AbstractThe production and purification of the secreted ectodomain of SARS-CoV-2 spike protein (S protein) were performed by transiently transfecting suspension-adapted Chinese hamster ovary cells (ExpiCHO). The method involved the separate addition of plasmid DNA expressing the S protein and polyethyleneimine to a suspension culture at a density of 5 × 106 cells/mL; and the subsequent addition of dimethyl sulfoxide at 2% (v/v).
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Sep 13, 2024 | 
nature.com | Ricardo C. Guerrero-Ferreira |Georgios Varnavides |Max Leo Leidl |Kelvin Lau |Alexander G. Myasnikov |Carsten Sachse | +2 more
AbstractCryo-transmission electron microscopy (cryo-EM) of frozen hydrated specimens is an efficient method for the structural analysis of purified biological molecules. However, cryo-EM and cryo-electron tomography are limited by the low signal-to-noise ratio (SNR) of recorded images, making detection of smaller particles challenging.
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May 28, 2024 | 
nature.com | Aaron S. Petruzzella |Marine Bruand |Albert Santamaria-Martínez |Natalya Katanayeva |Luc Reymond |Sandrine Georgeon | +6 more
AbstractCysteine cathepsins are a family of proteases that are relevant therapeutic targets for the treatment of different cancers and other diseases. However, no clinically approved drugs for these proteins exist, as their systemic inhibition can induce deleterious side effects. To address this problem, we developed a modular antibody-based platform for targeted drug delivery by conjugating non-natural peptide inhibitors (NNPIs) to antibodies.
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May 10, 2024 | 00119-x/fulltext?rss=yes&sz=64)
thelancet.com | Eric Lim |Harefield Hospitals |David Waller |Kelvin Lau
Research in contextEvidence before this studyWe conducted a review of the literature on PubMed from Jan 1, 1966, to Sept 1, 2017, restricted to randomised trials of extended pleurectomy decortication for malignant pleural mesothelioma, and none were identified.
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Apr 7, 2024 | 
allevents.in | Kelvin Lau
Outdoor Classes - ActiveSG Approved - HIIT ME!About this EventHIIT/Functional Fitness with Weights -Outdoor ActiveSG approved - For all levelsOutdoor Classes - ActiveSG Approved - HIIT ME!1-hour class focused on building strength and burning calories with ACE-CPT qualified trainer. Exercises designed for all levelsSmall classes for higher level of trainer-participant interaction.
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Jul 18, 2023 | 
biorxiv.org | Craig Fenwick |Priscilla Turelli |Kelvin Lau |Yoan Duhoo
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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Jul 7, 2023 | 
allevents.in | Kelvin Lau
Outdoor Classes - ActiveSG Approved - HIIT ME!About this Event1-hour class focused on building strength and burning calories with ACE-CPT qualified trainer. Exercises designed for all levelsSmall classes for higher level of trainer-participant interaction.
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Jul 4, 2023 | 
allevents.in | Kelvin Lau
Outdoor Classes - ActiveSG Approved - HIIT ME!About this EventHIIT/Functional Fitness with Weights -Outdoor ActiveSG approved - For all levelsOutdoor Classes - ActiveSG Approved - HIIT ME!1-hour class focused on building strength and burning calories with ACE-CPT qualified trainer. Exercises designed for all levelsSmall classes for higher level of trainer-participant interaction.
