Kerstin B Meyer

Nov 20, 2024 | nature.com | J. Patrick Pett |Kenny Roberts |Raphael Blain |Krzysztof Polanski |Peng He |Chuan Xu | +18 more

AbstractHuman embryonic bone and joint formation is determined by coordinated differentiation of progenitors in the nascent skeleton. The cell states, epigenetic processes and key regulatory factors that underlie lineage commitment of these cells remain elusive.

Aug 26, 2024 | journals.plos.org | Stathis Megas |Nadav Yayon |Kerstin B Meyer

Recent progress in the field of single-cell biology has led to an explosion of data providing molecular descriptions of individual cells and cell types, which are increasingly mapped into their tissue context. Dissociated single cells are now routinely profiled by combining multiple molecular features—mainly, the transcriptome, metabolome, and proteome. However, what is as yet missing is a better link to the morphological description of cells and tissues.

Aug 1, 2024 | nature.com | Kaylee B. Worlock |Lisa M Dratva |Masahiro Yoshida |Helen R. Wagstaffe |Laura Richardson |Josephine Barnes | +25 more

Correction to: Nature https://doi.org/10.1038/s41586-024-07575-x Published online 19 June 2024In the version of the article initially published, the Acknowledgements was missing the following text, which has now been added to the HTML and PDF versions of the article: “The authors gratefully acknowledge support from the UK Vaccine Taskforce of the Department of Business, Energy and Industrial Strategy of Her Majesty’s Government (BEIS).

Jun 17, 2024 | nature.com | Kaylee B. Worlock |Masahiro Yoshida |Krzysztof Polanski |Liam Bolt |Laura Richardson |Machaela Palor | +13 more

Correction to: Nature Microbiology https://doi.org/10.1038/s41564-024-01658-1, published online 15 April 2024In the version of the article initially published, Paolo De Coppi’s surname originally appeared as “DeCoppi”. In the third paragraph of the article, the callout to Extended Data Fig. 3i has been amended from Extended Data Fig. 4i. In the legend to Fig. 6, the description of panel m (“Summary figure highlighting the key findings from the study.

Apr 14, 2024 | nature.com | Kaylee B. Worlock |Masahiro Yoshida |Krzysztof Polanski |Liam Bolt |Laura Richardson |Machaela Palor | +13 more

AbstractChildren infected with SARS-CoV-2 rarely progress to respiratory failure. However, the risk of mortality in infected people over 85 years of age remains high. Here we investigate differences in the cellular landscape and function of paediatric (<12 years), adult (30–50 years) and older adult (>70 years) ex vivo cultured nasal epithelial cells in response to infection with SARS-CoV-2.