Laurent Abel

Jul 9, 2024 | cell.com | Laurent Abel |Paris Sorbonne Cité |Giles Laboratory |Rockefeller Branch

SummaryRegardless of microbial virulence (i.e., the global infection-fatality ratio), age generally drives the prevalence of death from infection in unvaccinated humans. Four mortality patterns are recognized: the common U- and L-shaped curves of endemic infections and the unique W- and J-shaped curves of pandemic infections. We suggest that these patterns result from different sets of human genetic and immunological determinants.

Oct 10, 2023 | liebertpub.com | Peng Zhang |Laurent Abel |Jean-Laurent Casanova |Rui Yang

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, New York, USA; Necker Hospital for Sick Children, Paris, France. Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Paris, France; Necker Hospital for Sick Children, Paris, France. University Paris Cité, Imagine Institute, Paris, France; Necker Hospital for Sick Children, Paris, France.