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Oct 9, 2024 | 
link.springer.com | Paris Sorbonne Cité
AbstractAdrenal Cushing represents 20% of cases of endogenous hypercorticism. Unilateral cortisol-producing adenoma (CPA), a benign tumor, and adrenocortical carcinoma (ACC), a malignant tumor, are more frequent than bilateral adrenal nodular diseases (primary bilateral macronodular adrenal hyperplasia (PBMAH) and primary pigmented nodular adrenal disease (PPNAD)). In cortisol-producing adrenal tumors, the signaling pathways mainly altered are the protein kinase A and Wnt/β-catenin pathways.
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Sep 26, 2024 | 
bmcmedicine.biomedcentral.com | Paris Sorbonne Cité
Physicians personalize care during treatment prescription, diagnosis or follow-up modalities, or consultation to enhance treatment engagement, respect patients’ priorities and preferences or reinforce patient‒physician relationships by using 40 markers reflecting patients’ psychosocial and contextual factors.
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Jul 9, 2024 | 00274-7&sz=64)
cell.com | Laurent Abel |Paris Sorbonne Cité |Giles Laboratory |Rockefeller Branch
SummaryRegardless of microbial virulence (i.e., the global infection-fatality ratio), age generally drives the prevalence of death from infection in unvaccinated humans. Four mortality patterns are recognized: the common U- and L-shaped curves of endemic infections and the unique W- and J-shaped curves of pandemic infections. We suggest that these patterns result from different sets of human genetic and immunological determinants.
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Jun 2, 2024 | 
link.springer.com | de Waele |Hôpital Saint-Louis |Paris Sorbonne Cité
As Presidents of the European Society of Intensive Care Medicine (ESICM), we are privileged to navigate the evolving landscape of intensive care medicine. ESICM has aimed to be a global society representing the intensive care unit (ICU) healthcare professionals (HCPs), enhancing care for patients and families worldwide. We are pleased to highlight our diverse activities and initiatives in pursuit of excellence and support for our members.
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May 17, 2024 | 
academic.oup.com | Paris Sorbonne Cité
Cognitive remediation (CR) is an effective therapy for the cognitive impact of mental illness, especially schizophrenia. Global efforts are being made to implement CR into routine mental health services with the aim of improving functional outcomes for the population of people recovering from mental illness. Implementation and dissemination of CR in heterogeneous settings require knowledge gleaned from formal implementation research and pragmatic experiential learning.
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May 14, 2024 | 
link.springer.com | Sidra Medicine |Istituto Giannina Gaslini |Paris Sorbonne Cité
AbstractAchondroplasia is a lifelong condition requiring lifelong management. There is consensus that infants and children with achondroplasia should be managed by a multidisciplinary team experienced in the condition. However, many people are lost to follow-up after the transition from paediatric to adult care, and there is no standardised approach for management in adults, despite the recent availability of international consensus guidelines.
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Mar 22, 2024 | 
karger.com | Paris Sorbonne Cité
Introduction: Neonatal portal vein thrombosis (PVT) is frequently related to umbilical venous catheterization (UVC), but risk factors remain unclear. This study aims to analyze the variables associated to PVT in near- to full-term newborns with UVC, with a focus on newborns exposed to controlled therapeutic hypothermia (CTH) for hypoxic ischemic encephalopathy (HIE). Methods: This is retrospective cohort study of infants delivered at or after 36 weeks and with a birthweight over 1,500 g.
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Mar 17, 2024 | 
bmcpediatr.biomedcentral.com | Paris Sorbonne Cité
The infant participants were part of a community-based, double-blind, randomized controlled trial on the effect of 2–3 recommended daily allowances (2 μg) of vitamin B12 on neurodevelopment, growth, and haemoglobin concentration [25, 26]. Main results from the study showed no effect of B12 supplementation on any of the clinical or functional outcomes, despite an excellent metabolic response [26].
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Feb 21, 2024 | 00761-2/abstract?rss=yes&sz=64)
thelancet.com | Paris Sorbonne Cité |Marion Caseris |Alexandra Ntorkou |Michael LEVY
A 2-month-old French infant with no medical history was admitted to an emergency department in Morocco for febrile partial seizure. She had been on holiday for 3 weeks and fever with vomiting started the day before admission. Hypotonia was noted without focal neurological sign or rash. C-reactive protein was at 117 mg/L, and haemogram, renal, and hepatic tests were normal.
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Jan 9, 2024 | 
onlinelibrary.wiley.com | Paul Bastard |Paris Sorbonne Cité |Giles Laboratory |Pediatric Hematology-Immunology
1 INTRODUCTION Not all individuals exposed to any given pathogen become infected and the impact of infection is highly variable, from silent infection to lethal disease. Many historically lethal infections can now be prevented or cured with modern medicine.
