Hua Zhang

1 month ago | advanced.onlinelibrary.wiley.com | Hua Zhang |Xiaogang Li |Mingzhe Zhang |Nan Zhang

Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202500950-sup-0001-SuppMat.pdf26.5 MB Supporting Information References 1, , , , Nat. Energy 2016, 1, 16132. 2, , , , , , Adv. Energy Mater. 2021, 11, 2002893. 3, , , , , , eScience 2021, 1, 44. 4, , , , , , , , , Angew. Chem., Int. Ed. 2024, 63, 202318785. 5, , , , , , , , , , , , , , , , eScience 2024, 4, 100222. 6, , , , , , , Adv. Mater.

1 month ago | nature.com | Hua Zhang |Lang Ding |Amy Hu |Xudong Shi |Penghsuan Huang |Haiyan Lu | +3 more

The spatial distribution of diverse biomolecules in multicellular organisms is essential for their physiological functions. High-throughput in situ mapping of biomolecules is crucial for both basic and medical research, and requires high scanning speed, spatial resolution, and chemical sensitivity. Here we developed a tissue-expansion method compatible with matrix-assisted laser desorption/ionization mass-spectrometry imaging (TEMI). TEMI reaches single-cell spatial resolution without sacrificing voxel throughput and enables the profiling of hundreds of biomolecules, including lipids, metabolites, peptides (proteins), and N-glycans. Using TEMI, we mapped the spatial distribution of biomolecules across various mammalian tissues and uncovered metabolic heterogeneity in tumors. TEMI can be easily adapted and broadly applied in biological and medical research, to advance spatial multi-omics profiling. Tissue-expansion method compatible with mass-spectrometry imaging (TEMI) enables the profiling of lipids, metabolites, peptides, proteins, and N-glycans in complex tissues with high spatial resolution, advancing spatially resolved multi-omics mapping.

Oct 23, 2024 | scijournals.onlinelibrary.wiley.com | Lin Zhang |Lin Dong |Hua Zhang |Xia Ma

• , , , and , Effect of the modifications on the physicochemical and biological properties of beta-glucan-a critical review . Molecules :57 ( ). • and , Impact of the molecular weight, viscosity, and solubility of β-glucan on in vitro oat starch digestibility . J Agric Food Chem : – ( ). • , , , , , et al., Effects of different sources of β-glucan on pasting, gelation, and digestive properties of pea starch . Food Hydrocoll : ( ).

Aug 28, 2024 | science.org | Loretah Chibaya |Ying Liu |Jie Ma |Liyin Zhang |Hua Zhang

Editor’s summaryLung regeneration after injury or transplantation is limited by fibrosis. Ma et al. showed that a subset of glycolytic endothelial cells that express Ras homolog family member J (Rhoj) was responsible for impaired lung regeneration and intussusceptive angiogenesis or split blood vessels in response to injury.

Apr 5, 2024 | onlinelibrary.wiley.com | Hua Zhang |Junjie Wei

In this paper, an susceptible–infected–susceptible (SIS) epidemic patch model with media delay is proposed at first. Then the basic reproduction number is defined, and the threshold dynamics are studied. It is shown that the disease-free equilibrium is globally asymptotically stable if and the disease is uniformly persistent if .