Marta C. Figueiredo

1 month ago | praderwillinews.com | Marisa Wexler |Joana Carvalho |Marta C. Figueiredo |Larry Luxner

Researchers have successfully used the gene-editing tool CRISPR to reactivate certain maternally-inherited genes that can compensate for the loss of the corresponding paternally-inherited genes in Prader-Willi syndrome (PWS). Done using lab-grown human stem cells with a PWS-causing mutation, the work showed that the one-time approach resulted in a sustained effect in the cells, according to the researchers.

1 month ago | copdnewstoday.com | Caroline Gainer |Steve Bryson |Marisa Wexler |Marta C. Figueiredo

I remember how hard it was to keep cars, or any other outdoor metal object, clean and looking good when I lived in the steel town of Weirton, West Virginia. That ongoing struggle reminds me of my ongoing battle with chronic obstructive pulmonary disease (COPD). In the late 1960s and early ’70s, nearly all of the steel mills in the upper Ohio Valley were fueled by metallurgical coal.

2 months ago | cysticfibrosisnewstoday.com | Lindsey Shapiro |Steve Bryson |Kristin Entler |Marta C. Figueiredo

Treatment with melatonin, a hormone best known for its sleep-promoting role, was found to normalize inflammatory responses to airway infection and reduce the burden of infection-causing bacteria in a mouse model of cystic fibrosis (CF), per new research by U.S. scientists. “Long-term systemic treatment with melatonin is an effective therapy in a CF mouse model that normalizes the response to airway infection,” the researchers wrote.

2 months ago | multiplesclerosisnewstoday.com | Leigh Nelson |Marisa Wexler |Ed Tobias |Marta C. Figueiredo

My husband and I are both considering early retirement. We’d discussed it for the past five years but hadn’t made any firm decisions. Last month, we decided that we needed to get serious about planning for it. We met with a financial adviser for retirement planning advice at our investment firm. The meeting lasted about an hour. Lots of questions were asked of us and lots of numbers were discussed.

2 months ago | multiplesclerosisnewstoday.com | Steve Bryson |Marta C. Figueiredo |Marisa Wexler

Nearly all adults with relapsing forms of multiple sclerosis (MS) said they are highly satisfied with the Sensoready autoinjector pen to self-administer Kesimpta (ofatumumab), according to a recent U.S. survey. High satisfaction was mainly driven by the reasonable administration time and ease of use, the researchers said. The study, “Real-world satisfaction and experience with injection and autoinjector device for ofatumumab indicated for multiple sclerosis,” was published in BMC Neurology.