Articles
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2 months ago |
mdpi.com | Michael Otto |Karsten Stahl |Erich Knoll |Chaokai Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Nov 18, 2024 |
insuedthueringen.de | Michael Otto
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Nov 12, 2024 |
nature.com | Yanan Wang |Yanfeng Liu |Michael Otto
AbstractDiverse post-translational modifications have been shown to play important roles in regulating protein function in eukaryotes. By contrast, the roles of post-translational modifications in bacteria are not so well understood, particularly as they relate to pathogenesis. Here, we demonstrate post-translational protein modification by covalent addition of lactate to lysine residues (lactylation) in the human pathogen Staphylococcus aureus.
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Nov 6, 2024 |
nature.com | Kensuke Ishiguro |Yoko Kusuya |Kazuyuki Matsushita |Toshibumi Taniguchi |Hidetoshi Igari |Naruhiko Ishiwada | +11 more
AbstractStaphylococcus aureus can cause outbreaks and becomes multi-drug resistant through gene mutations and acquiring resistance genes. However, why S. aureus easily adapts to hospital environments, promoting resistance and recurrent infections, remains unknown. Here we show that a specific S. aureus lineage evolved from a clone that expresses the accessory gene regulator (Agr) system to subclones that reversibly suppressed Agr and caused an outbreak in the hospital setting. S.
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May 21, 2024 |
nzcatholic.org.nz | Michael Otto
NZ Catholic, the national Catholic newspaper published by the Bishop of Auckland, is to cease its print publication at the end of June. A new monthly digital publication, which will retain the title NZ Catholic, will be developed and shared in the coming months. The publisher of NZ Catholic, Bishop Stephen Lowe, sent a letter dated to subscribers, supporters, readers and friends of NZ Catholic outlining the changes.
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