Miina Ollikainen

2 months ago | medrxiv.org | Alvaro Fernandez |Álvaro Fernández |Gabin Drouard |Teemu Palviainen |Miina Ollikainen

The authors have declared no competing interest. Funding: AO, KS, JK have been supported by the European Union Horizon Europe Research and Innovation programme under Grant Agreement number 101080117 (BETTER4U). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union. Neither the European Union nor the granting authority can be held responsible for them.

Apr 26, 2024 | medrxiv.org | Gabin Drouard |Fiona A. Hagenbeek |Miina Ollikainen |Zhili Zheng

The authors have declared no competing interest. Data collection of the EH-Epi sample has been supported by the Academy of Finland (Grants 265240, 263278, 308248, 312073, 336832 to JK and 297908 to MO) and the Sigrid Juselius Foundation (to MO). We want to acknowledge the participants and investigators of FinnGen study.

Jan 24, 2024 | nature.com | Eija K. Laakkonen |Urho M Kujala |Kirsi Pietiläinen |Terho Lehtimäki |Jaakko Kaprio |Miina Ollikainen | +1 more

AbstractMetabolic syndrome (MetS) is associated with premature aging, but whether this association is driven by genetic or lifestyle factors remains unclear. Two independent discovery cohorts, consisting of twins and unrelated individuals, were examined (N = 268, aged 23–69 years). The findings were replicated in two cohorts from the same base population. One consisted of unrelated individuals (N = 1 564), and the other of twins (N = 293).

Nov 6, 2023 | nature.com | Fang Fang |Bryan C Quach |Jesse Marks |Veronika V. Odintsova |Yujing Xia |Laura J. Bierut | +7 more

AbstractCannabis is widely used worldwide, yet its links to health outcomes are not fully understood. DNA methylation can serve as a mediator to link environmental exposures to health outcomes. We conducted an epigenome-wide association study (EWAS) of peripheral blood-based DNA methylation and lifetime cannabis use (ever vs. never) in a meta-analysis including 9436 participants (7795 European and 1641 African ancestry) from seven cohorts.