Peter Murray

Dec 9, 2024 | mdpi.com | Peter Murray |Jonathan Coffman |Franklin Garcia-Godoy

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Jul 10, 2024 | nature.com | Sainitin Donakonda |Jitao Zhang |Hannah Wintersteller |Martin Feuerherd |Juliane Siebourg-Polster |Carolin Mogler | +24 more

AbstractChronic hepatitis B virus (HBV) infection affects 300 million patients worldwide1,2, in whom virus-specific CD8 T cells by still ill-defined mechanisms lose their function and cannot eliminate HBV-infected hepatocytes3,4,5,6,7. Here we demonstrate that a liver immune rheostat renders virus-specific CD8 T cells refractory to activation and leads to their loss of effector functions.

Aug 31, 2023 | nature.com | Lukas T. Henneberg |Kheewoong Baek |Peter Murray |Matthias Mann |Sachdev S. Sidhu

AbstractThe cullin–RING ubiquitin ligase (CRL) network comprises over 300 unique complexes that switch from inactive to activated conformations upon site-specific cullin modification by the ubiquitin-like protein NEDD8. Assessing cellular repertoires of activated CRL complexes is critical for understanding eukaryotic regulation. However, probes surveying networks controlled by site-specific ubiquitin-like protein modifications are lacking.

Aug 4, 2023 | ribaj.com | Peter Murray

Entrepreneurial architect who nurtured and developed London's urban character with sympathetic modern buildings often in stone, concrete and brickAt the northern end of Tower Bridge is the entrance to a visitor centre leading to the elevated walkways which look down on the bascules below. The small cabin of glass and steel is an early work by Michael Squire, completed in 1993.

Jul 25, 2023 | architectsjournal.co.uk | Peter Murray

A few days before Michael Gove’s rejection of Marks & Spencer’s plans to demolish its Oxford Street store, New London Architecture (NLA) published its report on Circular London – an update on how the capital is doing in conforming to the London Plan 2021, which calls for materials to be ‘retained in use at their highest value for as long as possible and then reused or recycled, leaving a minimum of residual waste’.