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1 month ago | 
today.line.me | Wen Tsui |Zhou Saang |Tian Li
A U.S. federal judge has issued an injunction blocking the Trump administration from revoking the legal status of foreign students studying and working in the country. #XinhuaNews
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Jan 30, 2025 | 
today.line.me | Xiong Maoling |Hu Yousong |Liu Yutian |Tian Li
The Chinese Embassy in the United States said on Thursday that two Chinese citizens were among the victims in the mid-air collision of a passenger plane and a helicopter near Reagan National Airport Wednesday night. #XinhuaNews
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Jan 29, 2025 | 
today.line.me | Wang Chenxi |Zhou Saang |Tian Li
The newly installed capacity of renewable energy in 2024 accounted for 86 percent of China's total newly installed power capacity, while the cumulative installed capacity of renewable energy made up a record high of 56 percent of the nation's total, according to new data from the National Energy Administration (NEA). #XinhuaNews
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Jan 15, 2025 | 
nature.com | Tian Li |Stefan OP. Hofer |Geir Moholdt |Ádam Ignéczi |Konrad Heidler |Xiao Zhu | +1 more
A major uncertainty in predicting the behaviour of marine-terminating glaciers is ice dynamics driven by non-linear calving front retreat, which is poorly understood and modelled. Using 124919 calving front positions for 149 marine-terminating glaciers in Svalbard from 1985 to 2023, generated with deep learning, we identify pervasive calving front retreats for non-surging glaciers over the past 38 years. We observe widespread seasonal cycles in calving front position for over half of the glaciers. At the seasonal timescale, peak retreat rates exhibit a several-month phase lag, with changes on the west coast occurring before those on the east coast, coincident with regional ocean warming. This spatial variability in seasonal patterns is linked to different timings of warm ocean water inflow from the West Spitsbergen Current, demonstrating the dominant role of ice-ocean interaction in seasonal front changes. The interannual variability of calving front retreat shows a strong sensitivity to both atmospheric and oceanic warming, with immediate responses to large air and ocean temperature anomalies in 2016 and 2019, likely driven by atmospheric blocking that can influence extreme temperature variability. With more frequent blocking occurring and continued regional warming, future calving front retreats will likely intensify, leading to more significant glacier mass loss. This study analyses 124,919 glacier calving front positions to reveal widespread retreats and seasonal cycles across Svalbard since 1985, emphasising the crucial role of ice-ocean interaction and glaciers’ sensitivity to significant climate anomalies.
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Jan 14, 2025 | 
today.line.me | Cao Pengyuan |Zhou Saang |Tian Li
The Chinese government has released a list of measures to foster new growth points in the culture and tourism sector and boost related consumption. #XinhuaNews
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Dec 30, 2024 | 
nature.com | Tian Li |Shan Jiang |Yuanhao Dai |Xia Wu |Huihui Guo |Li Ren | +7 more
Marine cyclopianes are a family of diterpenoid with novel carbon skeleton and diverse biological activities. Herein, we report our synthetic and chemical proteomics studies of cyclopiane diterpenes which culminate in the asymmetric total synthesis of conidiogenones C, K and 12β-hydroxy conidiogenone C, and identification of Immunity-related GTPase family M protein 1 (IRGM1) as a cellular target. Our asymmetric synthesis commences from Wieland-Miescher ketone and features a sequential intramolecular Pauson-Khand reaction and gold-catalyzed Nazarov cyclization to rapidly construct the 6-5-5-5 tetracyclic skeleton. The stereocontrolled cyclopentenone construction is further investigated on complex settings to demonstrate its synthetic utility. Furthermore, using an alkyne-tagged conidiogenone C-derived probe, IRGM1, a master regulator of type I interferon responses, is identified as a key cellular target of conidiogenone C responsible for its anti-inflammatory activity. Preliminary mechanism of action studies shows that conidiogenone C activates IRGM1-mediate dysfunctional mitochondria autophagy to maintain mitochondria quality control of inflammatory macrophages. The cyclopiane diterpenoids are a class of complex natural products with unique carbon skeleton and diverse biological activities. Herein, the authors report the total synthesis and chemical proteomics studies of cyclopiane diterpenes which culminate in the asymmetric total synthesis of conidiogenones C, K and 12β-hydroxy conidiogenone C, and identification of Immunity-related GTPase family M protein 1 as a cellular target of conidiogenone C.
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Dec 11, 2024 | 
today.line.me | Tan Yixiao |Tian Li
The United Nations stands against any violation of the territorial integrity of Syria, a UN spokesperson said on Tuesday, after Israel seized a buffer zone in the Golan Heights following the collapse of Bashar al-Assad government. #XinhuaNews
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Dec 7, 2024 | 
today.line.me | Wang Yaguang |Wei Yukun |Yan Fujing |Zhou Saang |Tian Li
China's top economic planner said Saturday that funds raised through the 1-trillion-yuan (about 139 billion U.S. dollars) ultra-long special treasury bonds this year have all been allocated to support specific projects and programs. #XinhuaNews
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Dec 7, 2024 | 
today.line.me | Yoo Seungki |Zhou Saang |Tian Li
A majority of South Korea's ruling People Power Party lawmakers boycotted the vote on President Yoon Suk-yeol's impeachment motion, TV footage showed Saturday. #XinhuaNews
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Nov 8, 2024 | 
today.line.me | Chen Yongrong |Luo Sha |Shen Cheng |Tan Yixiao |Tian Li
Chinese lawmakers have approved a State Council bill on raising the ceiling on local government debt by 6 trillion yuan (about 840 billion U.S. dollars) to replace existing hidden debts, according to a press conference Friday. #XinhuaNews
