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Nov 18, 2024 | 
nature.com | Qiao Jin |Charalampos S Floudas |Fangyuan Chen |Yifan Yang |Jimeng Sun |Changlin Gong
AbstractPatient recruitment is challenging for clinical trials. We introduce TrialGPT, an end-to-end framework for zero-shot patient-to-trial matching with large language models. TrialGPT comprises three modules: it first performs large-scale filtering to retrieve candidate trials (TrialGPT-Retrieval); then predicts criterion-level patient eligibility (TrialGPT-Matching); and finally generates trial-level scores (TrialGPT-Ranking).
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Nov 17, 2024 | 
flipboard.com | Qiao Jin |Zifeng Wang |Charalampos S Floudas |Fangyuan Chen |Changlin Gong |Dara Bracken-Clarke | +4 more
4 hours agoHas AI Killed Graphic Design Jobs? The rapid advancement of generative AI technologies has undeniably transformed various sectors, including the field of graphic design.
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Nov 12, 2024 | 
nature.com | Haijie Han |Qiao Jin
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-53410-2, published online 18 October 2024In this article the affiliation ‘Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering, Taiyuan 030032, P.R. China’ for Qiao Jin was missing. The original article has been corrected.
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Nov 1, 2024 | 
arxiv.org | Qiao Jin |Karim Hanna |Yuzhang Xie |Carl Yang
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Oct 21, 2024 | 
pubs.rsc.org | Jinchao Zhao |Wenbin Dai |Angfeng Jiang |Qiao Jin
Simultaneous inhibition of heat shock proteins and autophagy enhances radiofrequency ablation of hepatocellular carcinoma†
Radiofrequency ablation (RFA) is a commonly used minimally invasive treatment for hepatocellular carcinoma (HCC). However, incomplete radiofrequency ablation (iRFA) promotes tumor progression and metastasis. There is an urgent need to develop innovative strategies to enhance the efficacy of iRFA.
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Oct 17, 2024 | 
nature.com | Haijie Han |Qiao Jin
AbstractFungi are very common infectious pathogens, which may cause invasive and potentially life-threatening infections. However, the efficacy of antifungal medications remains limited. Herein, a Cu2+-phenolic nanoflower is designed to combat fungal infections by combining cuproptosis and cell wall digestion. Firstly, protocatechuic acid (PA)-Cu2+ (PC) nanopetals are prepared by coordination interaction.
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Sep 30, 2024 | 
mdpi.com | Qiao Jin |Yong You |Haiyi Wang |Xueting Ma
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Sep 10, 2024 | 
nature.com | Yifan Yang |Qiao Jin
AbstractLarge language models like GPT-3.5-turbo and GPT-4 hold promise for healthcare professionals, but they may inadvertently inherit biases during their training, potentially affecting their utility in medical applications. Despite few attempts in the past, the precise impact and extent of these biases remain uncertain. We use LLMs to generate responses that predict hospitalization, cost and mortality based on real patient cases. We manually examine the generated responses to identify biases.
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Sep 8, 2024 | 
nature.com | Qiao Jin |Yiliang Zhou |Song Wang |Jordan G. Nestor |Ali Soroush |Zhiyong Lu | +1 more
AbstractLarge language models (LLMs) hold great promise in summarizing medical evidence. Most recent studies focus on the application of proprietary LLMs. Using proprietary LLMs introduces multiple risk factors, including a lack of transparency and vendor dependency. While open-source LLMs allow better transparency and customization, their performance falls short compared to the proprietary ones.
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Aug 22, 2024 | 
pubs.rsc.org | Fang Liu |Yongcheng Chen |Yue Huang |Qiao Jin
Nanomaterial-based therapeutics for enhanced antifungal therapy
The application of nanotechnology in antifungal therapy is gaining increasing attention. Current antifungal drugs have significant limitations, such as severe side effects, low bioavailability, and the rapid development of resistance. Nanotechnology offers an innovative solution to these issues. This review discusses three key strategies of nanotechnology to enhance antifungal efficacy.
