Soojin V. Yi

2 months ago | nature.com | DongAhn Yoo |Arang Rhie |Prajna hebbar |Francesca Antonacci |Glennis A. Logsdon |Brandon Pickett | +66 more

AbstractThe most dynamic and repetitive regions of great ape genomes have traditionally been excluded from comparative studies1,2,3. Consequently, our understanding of the evolution of our species is incomplete. Here we present haplotype-resolved reference genomes and comparative analyses of six ape species: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang.

Jun 3, 2024 | biorxiv.org | Hyeonsoo Jeong |Isabel Mendizabal |Soojin V. Yi |Basque Research

AbstractSignificant links between aging and DNA methylation are emerging from recent studies. On the one hand, DNA methylation undergoes changes with age, a process termed as epigenetic drift. On the other hand, DNA methylation serves as a readily accessible and accurate biomarker for aging. A key missing piece of information, however, is the molecular mechanisms underlying these processes, and how they are related, if any.