Stuart Williamson

1 month ago | nature.com | Valentina Cutano |Eleanor M. Wigmore |Lorna Hopcroft |Stuart Williamson |Cath Eberlein |Simon T. Barry

AbstractLoss of PTEN expression, via homozygous or hemizygous deletion, is common in PIK3CA mutant ER + BC tumors. We assessed reduction of PTEN protein expression on AKT inhibitor capivasertib efficacy in PIK3CA altered tumors. In PIK3CA altered, PTEN protein high models, PI3Kα and AKT inhibition was effective, however ablation and partial PTEN expression reduction attenuated PI3Kαi but not AKTi efficacy, alone or combined with fulvestrant.

Dec 1, 2024 | managementtoday.co.uk | Stuart Williamson

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Aug 11, 2024 | thescottishsun.co.uk | Stuart Williamson |Stuart Patterson |Harry Williamson

FIRE crews have been scrambled to a blaze at a Scots home that was hit by LIGHTNING. Emergency workers were deployed to the scene on Grampian View in Aviemore. Four fire engines and a height appliance were scrambled to the scene. Fortunately, no one was injured in the blaze. A Scottish Fire and Rescue Service spokesperson said: “We were alerted at 10am on Monday, 12 August, to reports of a dwelling fire following a lightning strike on Grampian View, Aviemore.

May 15, 2024 | beva.onlinelibrary.wiley.com | Stuart Williamson

Background Short incomplete sagittal fractures of the proximal phalanx are common in racehorses. Configurations vary; surgical planning has been performed using radiography which has limited ability to differentiate between common configurations. Computed tomographic (CT) imaging accurately maps fracture configuration and may be contributory to case management.

Feb 27, 2024 | science.org | Emily Erickson |Hao Cai |Leslie K. Ferrarelli |Inchul You |Grace Perry |Aurelien Dugourd | +11 more

Research ResourceCANCEREmily C. Erickson https://orcid.org/0000-0003-3494-2605, Inchul You, [...] , Grace Perry https://orcid.org/0000-0002-0404-9237, Aurelien Dugourd https://orcid.org/0000-0002-0714-028X, [...] , Katherine A. Donovan https://orcid.org/0000-0002-8539-5106, Claire Crafter https://orcid.org/0000-0001-6566-0868, Jeffrey W. Johannes https://orcid.org/0000-0001-7242-6682, Stuart Williamson https://orcid.org/0000-0002-5209-4796, Jennifer I.