Supinda Bunyavanich

2 months ago | jci.org | Young Kim |Supinda Bunyavanich

AbstractAsthma is a common chronic respiratory disease affecting people of all ages globally. The airway hosts diverse microbial communities increasingly recognized as influential in the development and disease course of asthma. Here, we review recent findings on the airway microbiome in asthma.

May 4, 2024 | sciencedirect.com | Supinda Bunyavanich |Kohei Hasegawa |Geoffroy Laumet |Eun-Kyung Kwon

IntroductionAtopic dermatitis (AD) is a chronic inflammatory skin disease characterized by dry, pruritic skin.1 Several studies have described nocturnal increases in scratching behavior, suggesting a role for circadian rhythms in modulating symptom severity.2,3 Circadian rhythms underlie skin physiology, such as DNA repair, transepidermal water loss, and keratinocyte proliferation.4,5 Understanding the mechanisms underpinning nocturnal increases in itch could improve therapeutic precision.

Oct 4, 2023 | nature.com | Ashley Budu-Aggrey |Anna Kilanowski |Maria K Sobczyk |Suyash Shringarpure |Ruth E. Mitchell |Kadri Reis | +68 more

AbstractAtopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery N = 1,086,394, replication N = 3,604,027), combining previously reported cohorts with additional available data.